Results 51 to 60 of about 5,915,019 (301)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Thriving amidst uncertainty: a financial blueprint for the public budget
This research explores strategies for thriving amidst uncertainty through a financial blueprint for public budgets, focusing on key factors like budgetary resilience (BR), stability (BS), sustainability (BSu), empowerment (BE), preparedness (BP ...
Enkeleda Lulaj
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Usability criteria for Business Intelligence Reports in the South African banking industry
Background: The South African banking sector is renowned as world-class, exhibiting ample capital, cutting-edge technology, robust infrastructure, and a rigorous regulatory and supervisory framework.
Pheladi A. Lebotsa +2 more
doaj +1 more source
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +3 more sources
Indicators of financial performance, especially financial ratio analysis, have become an important financial decision-support information used by the firm management and other stakeholders to assess financial stability and growth potential.
Petr Hájek +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Factors Affecting Unqualified Financial Reports [PDF]
The financial statements accompanied by independent auditors’ unqualified report which presents to capital market are used by interested beneficiary users. According to rules and regulations of the capital market, acceptance of the companies in the stock
Abbas Hoshi
doaj
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Relevance of parent entity financial reports
Executive Summary: This research addresses the issue of the extent to which parent entity financial information is needed by users of general purpose financial reports (GPFRs). It provides objective evidence aimed at assisting the Australian Accounting
Cotter, Julie
core +1 more source

