Results 61 to 70 of about 4,356,850 (307)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
New Safe Approximation of Ambiguous Probabilistic Constraints for Financial Optimization Problem
Discrete Dynamics in Nature and Society, 2019 In financial optimization problem, the optimal portfolios usually depend heavily on the distributions of uncertain return rates. When the distributional information about uncertain return rates is partially available, it is important for investors to ...
NingNing Du, Yan-Kui Liu, Ying Liu
doaj +1 more source
FINANCIAL RISK MANAGEMENT SYSTEM
International Journal of Business, Law and Political Science, 2023 Through the rapid development of the insurance market in Uzbekistan, by the end of 2022, respectively, compared to 2018, the share of insurance services in the gross domestic product (GDP) will be 2.0; the volume of total insurance premiums is 3.3; total assets of insurance organizations 2.1; to increase the number of types of insurance services by 1.7
openaire +1 more source
A Risk-Return Paradox: Risk, Performance-Based Pay and Performance [PDF]
, 1993 [Excerpt] In recent years, strategy researchers have examined the relationship between business risk and performance. The logic underlying this relationship is that organizations facing greater business risk seek to offset it with the prospect of higher ...
Bloom, Matthew C. +1 more
core +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Extending Basel Regulatory Capital Requirement under Economic Downturns [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2018 This paper studies credit risk management in banking industry and proposes a generic model for corporate loan portfolio loss distribution in economic downturns.
Amir Azamtarrahian, Saeed Asadi
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Modifying Sequential Monte Carlo Optimisation for Index Tracking to Allow for Transaction Costs
RisksManaging a portfolio whose value closely tracks an index by trading only in a subset of the index constituents involves an NP-hard optimisation problem.
Leila Hamilton-Russell +3 more
doaj +1 more source
Market Microstructure Effects on Firm Default Risk Evaluation
Econometrics, 2016 Default probability is a fundamental variable determining the credit worthiness of a firm and equity volatility estimation plays a key role in its evaluation.
Flavia Barsotti, Simona Sanfelici
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source