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The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Public Welfare Foundation - 2002 Annual Report [PDF]
Contains board chair and executive director's message, mission statement, program area and grant guidelines, financial statements, and lists of board members and ...
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We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
GASB Statement No. 31: Why No Controversy? [PDF]
Fair value reporting of investments in the financial statements of commercial enterprises is required under FASB Statement No. 115. The standard created much controversy when issued due to provisions that changes in fair values of certain investments ...
Hunt, George L.
core +3 more sources
Maqasid Syariah Sebagai Metode Membangun Tujuan Laporan Keuangan Entitas Syariah [PDF]
This article seeks to provide an interpretation of the concept of maqasid sharia then perform a constructive synthesis of various financial reporting purposes. Developing objective of financial statement, including sharia entity’s financial statement, is
M. Nur A. Birton
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Circular 02/10 : audit of the use of adult and community learning funds in local authorities from 1 April 2001 to 31 July 2002 [PDF]
"This circular provides guidance to local education authorities on the preparation of a statement showing the use of their funding allocations for adult and community learning for the period from 1 April 2001 to 31 July 2002.
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Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Lloyd A. Fry Foundation - 2005 Annual Report [PDF]
Contains mission statement, board chair's and executive director's messages, program information, grantee profiles, grants list, financial statements, grant guidelines, and lists of board members and ...
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