Results 51 to 60 of about 3,103,700 (302)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Annual Report and Financial Statements 2017 [PDF]

open access: yes, 2018
Annual report and financial statements HSE ...
Health Service Executive (HSE)
core  

2021 IFPRI audited financial statements

open access: yes, 2023
In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of IFPRI as of December 31, 2021 and 2020, and the changes in its net assets and its cash flows for the years ended in accordance ...
International Food Policy Research Institute (IFPRI)
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Financial statements analysis on Pfizer [PDF]

open access: yesSHS Web of Conferences
Financial reporting is a snapshot of the business activities and financial status of companies and is widely used for various purposes by different stakeholders, including insiders and outsiders of the company.
Wang Yutian
doaj   +1 more source

Pelatihan Teknik Menyusun Laporan Keuangan Untuk UMKM Agribisnis

open access: yesJurnal Inovasi Hasil Pengabdian Masyarakat, 2020
The goal to be achieved in this service program is to help compile and make financial statements CV. Kasih dan Sayang. Specific targets to be completed are knowledge and skills in preparing and formatting financial statements.
Mais Ilsan   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Analysis of Possibilities of Detectnig the Manipulation of Financial Statements in Terms of the IFRS and Czech Accounting Standards

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
The main objective of financial statements is to give information. The diversity of interests and objectives of individual groups of users and creators of financial statements presents the risk of manipulation of financial statements in the context of ...
Zita Drábková
doaj   +1 more source

2006 IFPRI audited financial statements

open access: yes, 2019
Financial statements and report of independent auditors as of December 31, 2006Non ...
International Food Policy Research Institute (IFPRI)
core  

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