Results 71 to 80 of about 6,594,563 (296)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Tatar women in the social life of Turkestan
The article presents information about Tatar women who played an important role in the social life of Turkestan in late 19th and early 20th centuries, for instance, how they founded charities and organised theatrical charity shows.
Dilfuza M. Nasretdinova
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Layout optimization for multi-bi-modulus materials system under multiple load cases [PDF]
Financial support from the National Natural Science Foundation of China (Grant No. 51179164) and the Australian Research Council (Grant No.
Cai, Kun +4 more
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Advancements in Higher Education for Latino(a)/Chicano(a) Doctorates [PDF]
Latinos(as)/Chicanos(as) are one of the minorities least represented in graduate school (Ramirez, 2016). Although there are few studies that primarily focus on the limitations Latinos(as)/Chicanos(as) students encounter in undergraduate and graduate ...
Chavez, Karina
core +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Russian Orthodox Church as the actor of modern politics of memory: the canonization discourse
On the basis of the analysis of various directions of canonization practices the article shows the transformation of the Russian Orthodox Church in the beginning of the 21st century into an active memory policy actor in Russia.
Batishev Roman Jurevich +2 more
doaj
Returning Home: Resettlement And Reintegration of Detainees Released From the U.S. Naval Base in Guantanamo Bay, Cuba [PDF]
Calls for a resettlement and reintegration policy, short-term financial assistance and support, and mental and physical health services for former detainees in partnership with local communities, and explains the policy rationale for U.S ...
core
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source

