Results 151 to 160 of about 1,918,508 (293)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Synergistic Roles of FAHD‐1 and PYC‐1 in Mitochondrial Function, Behavior, and Longevity in C. elegans

open access: yesAdvanced Biology, EarlyView.
FAHD‐1 and PYC‐1 catalyze opposing mitochondrial reactions that regulate oxaloacetate homeostasis in Caenorhabditis elegans. Using single and double knockouts, this study reveals that both enzymes shape locomotion, reproduction, respiration, and lifespan.
Riccardo Giaquinta   +3 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

Economic policy uncertainty and financial system efficiency. [PDF]

open access: yesHeliyon
Aman A   +5 more
europepmc   +1 more source

Micromechanical Characterization of 316L‐V4E Steel Transitions Produced by Electron Beam Powder Bed Fusion with Dual‐Hopper Alternating Layer Strategy

open access: yesAdvanced Engineering Materials, EarlyView.
This work applies High‐Speed Nanoindentation to study multi‐material transitions in powder bed fusion–electron beam melting components. The aim is to assess the mechanical gradients and interfacial behavior between American iron and steel institute 316L stainless steel and V4E tool steel in additively manufactured structures.
Laia Ortiz‐Membrado   +6 more
wiley   +1 more source

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