Results 31 to 40 of about 1,943,034 (249)

The offline cash puzzle solved by a local blockchain

open access: yesIET Blockchain
A major drawback in deploying central bank digital currencies (CBDC) is the offline puzzle, which requires that a CBDC must keep the liquidity provision given by cash, and, simultaneously, avoid double‐spending, cloning, and other issues.
Henrique de Carvalho Videira
doaj   +1 more source

Shifting the focus of world industrial development from European countries and North America to Asia

open access: yesВестник университета
Industry is the basis of economic development, therefore, studying the real sector allow us to assess the physical scale of the economy of individual countries and the world as a whole.
A. V. Ivanchenko
doaj   +1 more source

La Commissione Porter sul sistema bancario e finanziario canadese. (The Porter Commission on Canadian banking and finance)

open access: yesMoneta e Credito, 2014
Appointment in 1960 of the Royal Commission on Banking and Finance, now known as the Porter Commission, was precipitated by a growing dissatisfaction with the performance of the Canadian economy during the late 1950s when the rate of economic growth was ...
J.F. CHANT
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Uluslararası Tahvil Piyasasının Ekonomi Üzerindeki Etkisi; G7 Ülkeleri Örneği

open access: yesİstanbul Gelişim Üniversitesi Sosyal Bilimler Dergisi, 2019
Tarih sürecinde finansal sistemin sağladığı avantajlar, ülke gelişimine katkı sağladığını göstermektedir. Ülkelerin bu gelişiminde özellikle günümüzün finansal sisteminde, tahvil piyasasının gelişiminin hızlanması, ekonominin büyümesinde önemli olanak ...
Asef Yelghı
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Changing financial system architecture under the influence of the fintech market: A literature review

open access: yesManagement : Journal of Contemporary Management Issues, 2023
In the past seven decades, especially since the Global Financial Crisis, the financial system’s architecture has changed significantly around the world.
Natig Ismayilov, Emira Kozarević
doaj   +1 more source

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