Results 41 to 50 of about 596,237 (305)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Six-state review [PDF]

open access: yes
Year-to-date revenues for the first four months of FY2003 were above their FY2002 level in most New England states. Hit hard by dramatically diminished tax receipts and/or increased spending pressures, all six states closed FY2002 with deficits that had ...
E. Matthew Quigley
core   +3 more sources

BASEL III IMPACT ON BANKING SECTOR AND SMEs FINANCING

open access: yesStudies and Scientific Researches: Economics Edition, 2014
Financial crisis devastating consequences and effects started in 2008, lead to several reactions coming from the most important international organizations and entities. This article aims to present in a logic manner, synthetic, and easily understand why
Florin Mihai Magda
doaj   +1 more source

Credit risk assessment mechanism of personal auto loan based on PSO-XGBoost Model

open access: yesComplex & Intelligent Systems, 2022
As online P2P loans in automotive financing grows, there is a need to manage and control the credit risk of the personal auto loans. In this paper, the personal auto loans data sets on the Kaggle platform are used on a machine learning based credit risk ...
Congjun Rao, Ying Liu, Mark Goh
doaj   +1 more source

Advisor and Student Experiences of Summer Support for College-intending, Low-income high school graduates [PDF]

open access: yes, 2015
Summer melt occurs when students who have been accepted to college and intend to enroll fail to matriculate in college in the fall semester after high school.
Alexandra Chewning   +3 more
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Pembiayaan Konsumen Studi Tentang Hubungan Hukum Antara Konsumen dengan PT. Mitsui Leasing Capital Indonesia [PDF]

open access: yes, 2018
People consumption includes luxury goods, such as jewelry, personal vehicles. The acquisition of luxury goods is not always obtained with a single payment in full, given the price of luxury goods as mentioned above would be expensive.
, Dr. Kelik Wardiono, S.H., M.H.   +1 more
core   +2 more sources

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

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