Results 111 to 120 of about 345,158 (318)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Implementation challenges for achieving universal health coverage through social health protection scheme: what can we learn from Bangladesh?

International Journal of Qualitative Studies on Health & Well-Being
Background In Bangladesh, households experience high out-of-pocket healthcare expenditure, with below-poverty-line population being disproportionately affected.
Mohammad Wahid Ahmed, Quazi Nazmus Sakib, Md. Zahid Hasan, Gazi Golam Mehdi, Jahangir A.M. Khan, Ziaul Islam, Sayem Ahmed   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Health Care Financing Reform: Issues and Updates [PDF]

Generation of funds and its efficient utilization have remained as a challenge to health authorities. This issue presents the recent efforts on health care financing as well as the concerns regarding its coverage, efficiency and sustainability.
Health Policy Development Staff (DOH)
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Public finances, financing and taxation in Brussels

, 2009
This publication deals with the public finances in Brussels.
Cattoir, Philippe, Vaesen, Joost, Van Der Stichele, Géraldine, Verdonck, Magali, Zimmer, Pol   +4 more
openaire   +2 more sources

Payment compliance of informal sector workers in Indonesia National Health Insurance: a study on ability and willingness to pay

Health Economics Review
Background Currently, the Indonesian National Health Insurance (NHI) covers over 90% of the population. However, around 18% of the enrolees are inactive, failing to pay premiums regularly, with proportions varying across membership types.
Muhammad Syamsu Hidayat, Yudistira Hendra Permana, Diah Ayu Puspandari, Dedy Revelino Siregar, Hermawati Setyaningsih, Vini Aristianti, Wan Aisyah Baros, Zafria Atsna, Findri Fadlika, Azizah Boenjamin   +9 more
doaj   +1 more source

Trinity Law Framework: Health Insurance Taxonomy

Encyclopedia
Despite seven decades of international commitment—from the 1948 Universal Declaration of Human Rights through SDG 3.8—universal health coverage remains stubbornly out of reach.
David Mark Dror
doaj   +1 more source