Results 241 to 250 of about 487,212 (313)

How do stakeholders assess Jordan's institutional readiness for universal health coverage? An exploratory qualitative interview study in Jordan. [PDF]

BMJ Open
Alyahya MS, Abu Rumman S, Ibrahim M, Khatatbeh M.   +3 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Health taxes and universal health coverage in low- and middle-income countries: a scoping review of pathways, challenges and policy lessons. [PDF]

BMJ Open
Kurniawan DW, Dwirahmadi F, Byrnes J, Erku D, Kusuma D.   +4 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Assisted reproduction in the public sector: why secondary-level hospitals matter for equity and continuity of care. [PDF]

Front Reprod Health
Endara-Mina J, Bermúdez-Gavilanes J, Salazar FR, Manzano-Gallegos LA, Figueroa-Andrade JM, Ortega-Parraga DN, González-Naranjo DE, Maldonado-Montalvan F, Reytor-González C, Simancas-Racines D.   +9 more
europepmc   +1 more source

Equity in health financing in China: a national financing and benefit incidence analysis, 2013-2023. [PDF]

Lancet Reg Health West Pac
Chen T, Zhan P, Fu H.
europepmc   +1 more source

Emerging Governance Principles for Health-System Transformation in the Digital Era: A Policy Discourse Analysis of an Official Side Event of the Seventy-Ninth World Health Assembly. [PDF]

Health Care Sci
Yin H, Wu X, Song D, Wang Y, Liu X, Zhu H, Tian X, Fan X, Qiu Y, Ren M.   +9 more
europepmc   +1 more source

Financing and health system capacity for precision medicine in Asia: a six country landscape analysis. [PDF]

Health Aff Sch
Peh ALT, Teerawattananon Y, Yuen JXY, Charafi N, Tahapary DL, Leng J, Morton A, Li S, Kim WJ, Zilfalil BA, Hasbullah HH, Satproedprai N, Li ST, Ngeow JYY, Juang YR, Zhang Y, Hong M, Chen W.   +17 more
europepmc   +1 more source