Results 101 to 110 of about 107,874 (354)

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Testicular Fine Needle Aspiration in Evaluation of Male Infertility

Journal of Nepal Medical Association, 2009
Fine needle aspiration cytology of superficial as well as of deep seated lesions is now well recognized in diagnosis of neoplastic as well as nonneoplastic and inflammatory lesions.
Runa Jha, G Sayami
doaj   +1 more source

Increased 18F-FDG uptake mimicking thyroid cancer in a patient with Hashimoto's thyroiditis [PDF]

, 2018
.: We report the case of a 68-year-old patient with a known paravertebral malignant schwannoma, sent to us for postoperative staging. A combined whole-body PET/CT scan showed only poor 18F-fluorodeoxyglucose uptake in the region of the primary tumor but ...
Goerres, Gerhard, Kneifel, Stefan, Merrill, Griff, Padberg, Barbara-C, Schmid, Daniel, Stoeckli, Sandro   +5 more
core  

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Breast cancer risk is increased in the years following false-positive breast cancer screening [PDF]

, 2017
A small number of studies have investigated breast cancer (BC) risk among women with a history of false-positive recall (FPR) in BC screening, but none of them has used time-to-event analysis while at the same time quantifying the effect of false ...
Akl, Alamo-Junquera, Bangsboll-Andersen, Barlow, Blanch, Burrell, Castells, Castells, Christiansen, Ciatto, Duijm, Goossens, Haesook, Haward, Henderson, Hofvind, Marmot, Mathieu, Maxwell, Peeters, Perry, Purushotham, Putter, Verduijn, von Euler-Chelpin, von Euler-Chelpin   +25 more
core   +2 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Plonos adatos aspiracinė biopsija diagnozuojant skydliaukės vėžį

Lietuvos Chirurgija, 2007
Edita Mišeikytė Kaubrienė1,  Albertas Ulys1, Mantas Trakymas1,  Jolita Rimienė2 1 Vilniaus universiteto Onkologijos institutas, Santariškių g. 1, LT-08660 Vilnius 2 Valstybinis patologijos centras, Santariškių g.
Edita Mišeikytė Kaubrienė, Albertas Ulys, Mantas Trakymas, Jolita Rimienė   +3 more
doaj  

Thyroid Papillary Carcinoma Follicular Variant: Which Surgical Approach?

Haseki Tıp Bülteni, 2014
In general, fine needle aspiration biopsy (FNAB) is insufficient and inadequate in the diagnosis of follicular variant of thyroid papillary carcinoma. Especially in capsulated forms of the carcinoma, diagnostic difficulties are pronounced because of the ...
M. Gazi Yıldız, Sedat Aydın, Arif Şanlı, Mustafa Paksoy, Aylin Ege Gül   +4 more
doaj   +1 more source

Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]

, 2015
Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina, FRAMARINO DEI MALATESTA, Marialuisa, Iannini, Isabella, Masselli, Gabriele, Pecorella, Irene, Sammartino, Paolo   +5 more
core   +2 more sources

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source