Results 11 to 20 of about 32,491 (202)

Cosmological Constant in SUGRA Models with Degenerate Vacua

Universe, 2019
The extrapolation of couplings up to the Planck scale within the standard model (SM) indicates that the Higgs effective potential can have two almost degenerate vacua, which were predicted by the multiple point principle (MPP). The application of the MPP
Colin Froggatt, Holger Nielsen, Roman Nevzorov, Anthony Thomas   +3 more
doaj   +1 more source

Geometrical and physical conditions for skyrmion stability in a nanowire

AIP Advances, 2015
Skyrmions are promising information carriers in the next-generation storage and transmission devices. Appropriate design of the nanowire that permits the flow of skyrmions is, however, seldom studied. In this work, the geometrical and material parameters
C. P. Chui, Fusheng Ma, Yan Zhou
doaj   +1 more source

Spectral problem for the interface tensor: fine-tuned constants of physics

We pose a problem for mathematical physicists working at the intersection of spectral theory, quan- tum foundations, and the constants problem. The problem is precisely stated, with preconditions, a candidate mechanism, a falsifiable prediction, and a clear delineation of what would constitute a solution.
Theriault, Eric, DeepSeek A.I.
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Data-driven equation discovery of a sea ice albedo parametrisation [PDF]

The Cryosphere
In many sea ice models, a single-category, zero layer thermodynamic scheme is employed, in which sea ice albedo is prescribed based on surface types depending on snow cover, surface temperature, or sea ice thickness.
D. W. Atmojo, D. W. Atmojo, K. Weigel, K. Weigel, A. Grundner, M. M. Holland, D. Sidorenko, V. Eyring, V. Eyring   +8 more
doaj   +1 more source

Nonergodic Delocalized States for Efficient Population Transfer within a Narrow Band of the Energy Landscape

Physical Review X, 2020
We address the long-standing problem of the structure of the low-energy eigenstates and long-time coherent dynamics in quantum spin-glass models. Below the spin-glass freezing transition, the energy landscape of the spin system is characterized by a ...
Vadim N. Smelyanskiy, Kostyantyn Kechedzhi, Sergio Boixo, Sergei V. Isakov, Hartmut Neven, Boris Altshuler   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy

Advanced Engineering Materials, EarlyView.
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang, Jianxiang Zhao, Zhaoqi Chen, Hao Gong, Yinsen Yan, Junlei Tao, Yong Yang   +6 more
wiley   +1 more source