Results 61 to 70 of about 75,321 (266)

Hydro-abrasive resistance and mechanical properties of rubberized concrete

Građevinar, 2014
Results obtained by testing hydro-abrasive resistance and mechanical properties of concrete with rubber granules are presented in the paper. Fine river aggregate is replaced with 10, 20, and 30 percent of recycled granulated rubber (with respect to the ...
Zoran Grdić, Gordana Topličić-Curčić, Nenad Ristić, Dušan Grdić, Petar Mitković   +4 more
doaj   +1 more source

Prediction of Flexural Strength of Concrete Produced by Using Pozzolanic Materials and Partly Replacing NFA by MS [PDF]

Journal of Soft Computing in Civil Engineering, 2019
The use of huge quantity of natural fine aggregate (NFA) and cement in civil construction work which have given rise to various ecological problems. The industrial waste like Blast furnace slag (GGBFS), fly ash, metakaolin, silica fume can be used as ...
Kiran Mane, Dilip Kulkarni, K. Prakash
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Alternative Fine Aggregates to Natural River Sand for Manufactured Concrete Ensuring Circular Economy

Construction Materials
To address SDG12 (ensure sustainable consumption and production patterns), and to provide technical evidence for alternative concrete constituents to traditional natural river sand, stone fine aggregate (SFA), brick fine aggregate (BFA), ladle-refined ...
Tarek Uddin Mohammed, Md. Aktaruzzaman Rony, Mohammad Zunaied Bin Harun, Naba Uddin, Debasish Saha, Md. Nafiur Rahman, Aziz Hasan Mahmood   +6 more
doaj   +1 more source

Environmental Evaluation of Concrete Containing Recycled and By-Product Aggregates Based on Life Cycle Assessment

Applied Sciences, 2020
This study aims to compare the potential environmental impact of the manufacture and production of recycled and by-product aggregates based on a life cycle assessment and to evaluate the environmental impact and cost when they are used as aggregates in ...
Seungjun Roh, Rakhyun Kim, Won-Jun Park, Hoki Ban   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Compressive Strength of Concrete made from Natural Fine Aggregate Sources in Minna, Nigeria

Arid Zone Journal of Engineering, Technology and Environment, 2017
This work presented an investigation of concrete developed from five fine aggregate sources in Minna, Niger state, Nigeria. Tests conducted on the fine aggregate samples included specific gravity, sieve analysis, bulk density and moisture content.
M. Abdullahi, A. Yakubu, J. I. Aguwa
doaj  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source