Results 31 to 40 of about 1,698,103 (335)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Analysis of residential satisfaction in the conversion of Beijing’s stock buildings into rental housing

Scientific Reports
This paper investigates the residential satisfaction levels of tenants living in rental housing converted from non-residential stock buildings in Beijing.
Xuefen Hu, Jian Suo, Ningbo Kou, Mengxue Wu, Shiyu Wang   +4 more
doaj   +1 more source

The Sculpture Question [PDF]

, 2014
Paper presented, and subsequent panel discussion with: Jordan Baseman, artist and Head of Sculpture, Royal College of Art; Anna Moszynska, art historian and author, Sculpture Now; Emma Hart, artist; Jon Wood, Research Curator, Henry Moore Institute, and ...
Hart, Emma
core  

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Multi-Objective Optimization Design for Cold-Region Office Buildings Balancing Outdoor Thermal Comfort and Building Energy Consumption

Energies
Performance parameters and generative design applications have redefined the human–machine collaborative relationship, challenging traditional architectural design paradigms and guiding the architectural design process toward a performance-based design ...
Fei Guo, Shiyu Miao, Sheng Xu, Mingxuan Luo, Jing Dong, Hongchi Zhang   +5 more
doaj   +1 more source

Multianalytical approach for the analysis of the Codices Millenarius Maior and Millenarius Minor in Kremsmuenster Abbey, Upper Austria

Heritage Science, 2018
Two precious Carolingian manuscripts kept in the library of Kremsmuenster Abbey in Upper Austria were subject of investigation. The well-known Codices Millenarius Maior (Inv. No. CC Cim 1, Fig. 1a) and Millenarius Minor (Inv. No. CC Cim 2, Fig.
Bernadette Frühmann, Federica Cappa, Wilfried Vetter, Manfred Schreiner, Father Petrus   +4 more
doaj   +1 more source

The Teaching Landscapes in Creative Subjects: Fine Art Area Report [PDF]

, 2009
Report written as part of a research project (The Pedagogy of Fine Art) exploring contemporary pedagogy and attitudes to teaching within the fine art subject ...
Fortnum, Rebecca, Houghton, Nicholas
core  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Serotonergic and Dopaminergic Function in Neuropsychiatrically Asymptomatic People With HIV on Antiretroviral Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau, Anna Lyndaker, Swati Shah, Paul Wakim, Amelia Mitchell, Cynthia Monroe, Alan Kim, Tracy L. Cropper, Govind Nair, Joseph Snow, Bryan R. Smith, Avindra Nath, Dima A. Hammoud   +12 more
wiley   +1 more source

Environmental Benefits Evaluation of a Bike-Sharing System in the Boston Area: A Longitudinal Study

Urban Science
With increasing concerns over climate change and air pollution, sustainable transportation has become a critical component of modern city planning. Bike-sharing systems have emerged as an eco-friendly alternative to motorized transport, contributing to ...
Mengzhen Ding, Shaohua Zhang, Lemei Li, Yishuang Wu, Qiyao Yang, Jun Cai   +5 more
doaj   +1 more source