Results 121 to 130 of about 353,518 (312)
A Definition for Fine Tuning in Analogy to the Chaos [PDF]
Anthropic principles were grown from the problem of fine tuning. Although anthropic principles have been discussed in cosmology for years there is no exact definition for fine tuning. Starting from the supposed similarity in the topologies of chaotic and fine tuned regions of the proper phase spaces, we introduce an alternative Lyapunov indicator for ...
arxiv
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
The benefits of using natural pozzolan as cement replacement are often associated with shortcomings such as the need to moist-curing for longer time and a reduction of strength at early ages.
Aref M. al-Swaidani+2 more
doaj +1 more source
Locales, the locally fine construction and formal spaces [PDF]
We investigate the connection between the spatiality of locale products and the earlier studies of the author on the locally fine coreflection of the products of uniform spaces. After giving a historical introduction and indicating the connection between spatiality and the locally fine construction, we indicate how the earlier results directly solve ...
arxiv
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Temperature gradients due to heat of hydration of cement can cause cracking and present serious structural and serviceability concerns in concrete structures.
P C Graham, Y Ballim, J B Kazirukanyo
doaj
Contribution of Fineness Level of Fly Ash to the Compressive Strength of Geopolymer Mortar
The development of geopolymers has allowed the flash as the substitution of cement in the application of concrete. Therefore, this will be very useful considering the quite abundant by-product materials from power plants burning coal in South Sumatera ...
Firdaus, Yunus Ishak, Rosidawani
doaj +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source