Visual physical simulation experiment of coal fines migration and blockage removal in fractures
Meitan xuebaoThe deposition of coal fines in fractures can reduce the fracture conductivity and restrict the efficient and stable development of coalbed methane wells.
Yingchun WEI +7 more
doaj +1 more source
Laboratory study on the effects of hydraulic and granulometric parameters on the response of granular soil to internal erosion [PDF]
, 2019 Erosion is a major environmental problem to agricultural land as well as to civil engineering infrastructures. Rainwater infiltration into granular soils can lead to the migration of fine particles by suffusion.
BENDANI, Karim +2 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Immigration-Related Worksite Enforcement: Performance Measures [PDF]
, 2015 [Excerpt] According to the estimates by the Department of Homeland Security (DHS), some 11.4 million unauthorized immigrants were living in the United States in 2012.1 The Pew Research Center’s unauthorized alien population estimate for 2012 was 11.2 ...
Bruno, Andorra
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Journal of Marine Science and EngineeringFines migration and clogging in porous media have significant implications for engineering applications. For example, during the extraction of marine gas hydrates, fines migration can lead to pore clogging and reduced permeability.
Shuang Cindy Cao +4 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Balancing Hydraulic Fracturing’s Environmental and Economic Impacts: The Need for a Comprehensive Federal Baseline and the Provision of Local Rights [PDF]
, 2013 Reliable evaluation methods is needed to ensure that investments in energy conservation measures (ECMs) and the construction of new energy efficient buildings lives up to the promised and expected performance.
Garmezy, Adam
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Impact of pore fluid chemistry on fine‐grained sediment fabric and compressibility [PDF]
, 2018 Author Posting. © American Geophysical Union, 2018. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution.
Cao, Shuang C. +4 more
core +1 more source