Results 51 to 60 of about 147,751 (305)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Cold sensitivity test for individuals with non-freezing cold injury: the effect of prior exercise [PDF]

, 2013
BACKGROUND: One of the chronic symptoms of non-freezing cold injury (NFCI) is cold sensitivity. This study examined the effects of prior exercise on the response to a cold sensitivity test (CST) in NFCI patients with the aim of improving diagnostic ...
Eglin, Clare, Golden, F., Tipton, Mike
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Sensory restoration of the critical border of the small finger by an emergency heterodigital nerve transfer after circular saw injury

Acta Marisiensis - Seria Medica
Traumatic nerve injuries involving the distal part of the upper extremity may significantly affect the function of the hand if left untreated. An alternative to nerve autografts for treating digital nerve injuries are nerve transfers.
Ioncioaia Bogdan, Mironica Andreea, Filip Claudiu Ioan   +2 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Finite element analysis of human finger injury under blunt impact: Subcutaneous hemorrhage and laceration

Results in Engineering
Although previous studies have investigated soft tissue injuries using experiments or computer simulations, few have addressed injury thresholds specific to the human finger, despite the high frequency of finger-related incidents in human-robot ...
Yoichi Asano, Rajaei Nader, Takahiro Issiki, Yu-ki Higuchi, Yoji Yamada, Tatsuo Fujikawa, Fusako Sato   +6 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Avoidable injuries in pediatric hand fractures: a 30-year review of compensation claims in Finland

Acta Orthopaedica
Background and purpose: We aimed to evaluate the risk, causes, and compensation outcomes of avoidable injuries in pediatric hand fractures. Methods: All compensation claims submitted to the Finnish Patient Insurance Centre (PIC) for pediatric hand ...
Caroline C  Dikert, Petra Grahn, Yrjänä Nietosvaara   +2 more
doaj   +1 more source

Functional results following surgical repair of post-traumatic hand tendon injuries [PDF]

, 2016
Introduction: The study aims to determine whether early physical therapy following hand tendon repair gives better results and to look at any possible limiting factors locally.
Bugeja, Mark, Mifsud, Max, Zammit, Jason
core