Results 51 to 60 of about 2,154,749 (375)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Flexible and highly sensitive ionic skins with multiple dielectric layers for finger joint bending angle monitoring

open access: yesAlexandria Engineering Journal, 2021
Finger joint motion monitoring is crucial for rehabilitation training and ergonomics. Based on a multilayer dielectric structure, this study proposed flexible and highly sensitive ionic skins (sensors) for the measurement of the bending angles of finger ...
Na Ni
doaj  

Biomimetic Artificial Joints Based on Multi-Material Pneumatic Actuators Developed for Soft Robotic Finger Application

open access: yesMicromachines, 2021
To precisely achieve a series of daily finger bending motions, a soft robotic finger corresponding to the anatomical range of each joint was designed in this study with multi-material pneumatic actuators. The actuator as a biomimetic artificial joint was
Shumi Zhao   +7 more
doaj   +1 more source

Functionally Divided Manipulation Synergy for Controlling Multi-fingered Hands [PDF]

open access: yesarXiv, 2020
Synergy supplies a practical approach for expressing various postures of a multi-fingered hand. However, a conventional synergy defined for reproducing grasping postures cannot perform general-purpose tasks expected for a multi-fingered hand. Locking the position of particular fingers is essential for a multi-fingered hand to manipulate an object. When
arxiv  

Artificial finger joint replacement due to a giant cell tumor of the tendon sheath with bone destruction: A case report

open access: yesOncology Letters, 2015
The current study presents the case of a 25-year-old male who developed tumor recurrence of the proximal phalange of the ring finger on the right hand 4 years after partial tumor resection surgery.
Hui Lu   +4 more
semanticscholar   +1 more source

Histogram Based Synovitis Scoring System Using Ultrasound Images of Rheumatoid Arthritis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: The gray scale Ultrasound (US) imaging aids in assessing activity of Rheumatoid arthritis condition through classification of synovitis and is able to estimate the disease progression.
RJ Hemalatha, V Vijayabaskarin
doaj   +1 more source

Finger Kinematics during Human Hand Grip and Release

open access: yesBiomimetics, 2023
A bionic robotic hand can perform many movements similar to a human hand. However, there is still a significant gap in manipulation between robot and human hands.
Xiaodong Li   +5 more
doaj   +1 more source

A Reversed Inset Toe PIPJ Vascularized Joint Transfer for Finger PIPJ Composite Defect Reconstruction

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Background:. Free vascularized joint transfers (VJT) are indicated for reconstruction of a composite defect of the finger joints. When the bone defect involves the proximal interphalangeal joint (PIPJ) and the full length of the middle phalanx, using the
Yu-Te Lin, MD, MS   +1 more
doaj   +1 more source

Digital instability of a confined elastic meniscus [PDF]

open access: yesProceedings of the National Academy of Science, 110, 12545-12548 (2013), 2013
Thin soft elastic layers serving as joints between relatively rigid bodies may function as sealants, thermal, electrical, or mechanical insulators, bearings, or adhesives. When such a joint is stressed, even though perfect adhesion is maintained, the exposed free meniscus in the thin elastic layer becomes unstable, leading to the formation of spatially
arxiv   +1 more source

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