Results 181 to 190 of about 84,152 (317)

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

DNA fingerprinting.

, 2003
This report informs the reader about the importance of DNA fingerprinting and the trials and tribulations of accepting this new forensic science in the courtroom.
Hayden, Matthew Steven, Caron, Lizabeth K., French, Brian Eric   +2 more
core  

Development and application of core collection, KASP markers and SNP-based DNA fingerprinting in <i>Ziziphus jujuba</i>. [PDF]

Front Plant Sci
Shen B, Chen Y, Li K, Jin J, Yuan Y, Li L, Chen C, Fan D, Hao Q, Yang L.   +9 more
europepmc   +1 more source

Decoupling Intrinsic Molecular Efficacy From Platform Effects: An Interpretable Machine Learning Framework for Unbiased Perovskite Passivator Discovery

Advanced Science, EarlyView.
This study establishes an interpretable machine learning framework that disentangles the intrinsic molecular efficacy of passivators from experimental platform effects—enabling unbiased, high‐throughput discovery of effective perovskite surface modifiers.
Jing Zhang, Ziyuan Li, Shan Gao, Zhen Zhu, Jing Wang, Xiangmei Duan   +5 more
wiley   +1 more source

DNA FINGERPRINTING

, 2012
Within the last two decades, the arrival of new technologies such as DNA fingerprinting and databases, have strongly affected society and our judicial system.
Machlin, Emily S, White, Kevin Michael, Rodriguez, Nicolas A.   +2 more
core  

Electric‐Current‐Induced Phase Transformation in Cu6Sn5 Below Its Equilibrium Transition Temperature

Advanced Science, EarlyView.
Electric current induces a monoclinic‐to‐hexagonal phase transformation in Cu6Sn5 at a measured bulk temperature of ∼120°C, below the equilibrium transition temperature. Ex situ synchrotron x‐ray diffraction, TEM, and matched thermal controls show that current stressing promotes the formation of a retained hexagonal η‐phase post‐stress state not ...
Shih‐kang Lin, Shubhayan Mukherjee, Yu‐chen Liu, Jun Mizuno   +3 more
wiley   +1 more source

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

Advanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu, Xiujuan Hu, Shengqun Shi, Bowen Li, Zhixing Ge, Yunchen Long, Chaochao Sun, Annan Chen, Bingbing Gao, Lianbo Guo, Condon Lau, Wei Luo, Chwee Teck Lim   +12 more
wiley   +1 more source

Rapid Raman Fingerprinting Identification of <i>Listeria monocytogenes</i> via Immunomagnetic Enrichment Coupled with Droplet-Shrinkage-Assisted SERS. [PDF]

Anal Chem
He H, Liang P, Lin Y, Li X, Xue D, Wu M, Zhao F, Ye K, Li C, Zhou G, Tang C.   +10 more
europepmc   +1 more source

Temperature‐Driven Emission Redistribution of Yb2+ in SrB4O7 Enables Highly Sensitive Optical Thermometry Supported by Multiple Linear Regression

Advanced Science, EarlyView.
A novel optical thermometer exploits the rare UV emission of Yb2+ ions in a SrB4O7 host, enabling highly sensitive, non‐contact temperature measurements from 80 to 420 K. The applied multiple linear regression (MLR) analysis results in a multiple increase in the resulting temperature sensitivity.
Fang Zhao, Teng Zheng, Przemysław Woźny, Miguel A. Hernández‐Rodríguez, Shiqing Xu, Inocencio R. Martín, Marcin Runowski   +6 more
wiley   +1 more source

Diverse intracellular trafficking of insulin analogs by machine learning-based colocalization and diffusion analysis. [PDF]

iScience
Bleshøy SV, Kæstel-Hansen J, Nielsen AJ, Mishra NK, Jensen KJ, Hatzakis NS.   +5 more
europepmc   +1 more source