Results 201 to 210 of about 111,877 (248)

Selection profiles in RNA viruses reflect the characteristics of viruses more than individual proteins. [PDF]

PLoS Pathog
Muñoz-Baena L, Castelán-Sánchez HG, Bagherichimeh S, Magbor P, Rojas-Vargas J, Khan A, Olabode AS, Poon AFY.   +7 more
europepmc   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Domain-Aware Feature Engineering for Prediction of Molecular Optical Interference in High-Throughput Screening. [PDF]

J Chem Inf Model
Stefaniak F.
europepmc   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

Physicochemical, Predicted ADME, and Structural Positioning of Azelaic Acid Within an Endocrine Oncology Reference Framework. [PDF]

Pharmaceuticals (Basel)
Jurj ED, Voicu A, Colibășanu D, Voicu M, Nicolov M, Udrescu L.   +5 more
europepmc   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

Ligand Design Using Unique Conformations to Preferentially Dock a Specific Site on Collagen-Bound MMP1. [PDF]

Biology (Basel)
Nash A, Harms C, Sarkar SK.
europepmc   +1 more source

Engineering Borophene Band Structure Through Thickness

Advanced Science, EarlyView.
Borophene grown on W(110) shows a thickness‐dependent evolution of its structural and electronic properties. Surface microscopy, diffraction, XPS, and ARPES reveal distinct monolayer and bilayer phases. The formation of the second layer is accompanied by structural reconstruction, changes in chemical properties, and new ARPES features, demonstrating ...
Matteo Jugovac, Marcin Szpytma, Tevfik Onur Menteş, Andrea Locatelli, Iulia Cojocariu   +4 more
wiley   +1 more source

Assessing the Generalizability of Machine Learning and Physics-Based Methods with DNA-Encoded Libraries. [PDF]

J Chem Inf Model
Dolorfino M, Santos Perez D, Fu Y, Lin SH, McCarty S, O'Meara MJ, Sztain T.   +6 more
europepmc   +1 more source