Results 91 to 100 of about 991,859 (385)

Change in the repair cycle of excavator fingers

open access: yesГорное оборудование и электромеханика
The volumes of mined coal are affected by both the amount mining equipment (distribution by excavator-truck complex) and reliability associated with the smooth operation the open pit.
Levashova E.E.
doaj   +1 more source

Coxins interfalangeanos sobre paquidermodactilia Interphalangeal pads on pachydermodactyly

open access: yesAnais Brasileiros de Dermatologia, 2004
Coxins interfalangeanos são nodulações ceratósicas, de limites precisos, com aproximadamente um centímetro de diâmetro, geralmente sobre as articulações interfalangenas das mãos.
José Marcos Pereira   +2 more
doaj   +1 more source

CHANCRE OF THE FINGER [PDF]

open access: yesJournal of the American Medical Association, 1915
J. C., white man, aged 38, single, waiter, a native of Switzerland, Feb. 18, 1912, noticed a swelling just to the inner side of the nail of the right index-finger. This increased in size along the inner side of the terminal phalanx and became so painful that after ten days the patient found it necessary to stop work.
openaire   +3 more sources

When Fingers Meet Strings [PDF]

open access: yes, 2019
There is a great need for a current and comprehensive curriculum for young harp students. Most of the available instruction books and volumes are over half a century old, and while they have held up in some ways to the test of time, in many others they ...
Gibson, Kara Joy
core   +1 more source

Hand and foot pressures in the aye-aye (Daubentonia madagascariensis) reveal novel biomechanical trade-offs required for walking on gracile digits [PDF]

open access: yes, 2010
Arboreal animals with prehensile hands must balance the complex demands of bone strength, grasping and manipulation. An informative example of this problem is that of the aye-aye (Daubentonia madagascariensis), a rare lemuriform primate that is unusual ...
Ancrenaz   +66 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Structural classification of zinc fingers: survey and summary.

open access: yesNucleic Acids Research, 2003
Zinc fingers are small protein domains in which zinc plays a structural role contributing to the stability of the domain. Zinc fingers are structurally diverse and are present among proteins that perform a broad range of functions in various cellular ...
S. Krishna, I. Majumdar, N. Grishin
semanticscholar   +1 more source

Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198. [PDF]

open access: yesPLoS ONE, 2014
SUMO-binding proteins interact with SUMO modified proteins to mediate a wide range of functional consequences. Here, we report the identification of a new SUMO-binding protein, ZNF261.
Catherine M Guzzo   +7 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Differential Role of Snail1 and Snail2 Zinc Fingers in E-cadherin Repression and Epithelial to Mesenchymal Transition*

open access: yesJournal of Biological Chemistry, 2013
Background: Snail1 and Snail2 are highly homologous zinc finger transcriptional repressors exhibiting divergent functions. Results: Snail1 and Snail2 use a unique set of zinc fingers to execute their biological activity.
Ana Villarejo   +4 more
semanticscholar   +1 more source

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