Results 91 to 100 of about 983,509 (385)

CHANCRE OF THE FINGER [PDF]

open access: yesJournal of the American Medical Association, 1915
J. C., white man, aged 38, single, waiter, a native of Switzerland, Feb. 18, 1912, noticed a swelling just to the inner side of the nail of the right index-finger. This increased in size along the inner side of the terminal phalanx and became so painful that after ten days the patient found it necessary to stop work.
openaire   +3 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198. [PDF]

open access: yesPLoS ONE, 2014
SUMO-binding proteins interact with SUMO modified proteins to mediate a wide range of functional consequences. Here, we report the identification of a new SUMO-binding protein, ZNF261.
Catherine M Guzzo   +7 more
doaj   +1 more source

When Fingers Meet Strings [PDF]

open access: yes, 2019
There is a great need for a current and comprehensive curriculum for young harp students. Most of the available instruction books and volumes are over half a century old, and while they have held up in some ways to the test of time, in many others they ...
Gibson, Kara Joy
core   +1 more source

Kinesiological study of the push-up motion in spinal cord injury patients: involving measurement of hand pressure applied to a force plate. [PDF]

open access: yes, 2002
We studied the pressure exerted by hands during push-ups in 21 paraplegic and 2 tetraplegic patients employing 4 different hand positions. In the fingers-spread position, the initial force exerted was a vertical force (Fz), followed by a medio-lateral ...
Kotani, Yasuhiro, Tokuhiro, Akihiro
core   +1 more source

Structural classification of zinc fingers: survey and summary.

open access: yesNucleic Acids Research, 2003
Zinc fingers are small protein domains in which zinc plays a structural role contributing to the stability of the domain. Zinc fingers are structurally diverse and are present among proteins that perform a broad range of functions in various cellular ...
S. Krishna, I. Majumdar, N. Grishin
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Differential Role of Snail1 and Snail2 Zinc Fingers in E-cadherin Repression and Epithelial to Mesenchymal Transition*

open access: yesJournal of Biological Chemistry, 2013
Background: Snail1 and Snail2 are highly homologous zinc finger transcriptional repressors exhibiting divergent functions. Results: Snail1 and Snail2 use a unique set of zinc fingers to execute their biological activity.
Ana Villarejo   +4 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Fingering Instability in Combustion

open access: yes, 1997
A thin solid (e.g., paper), burning against an oxidizing wind, develops a fingering instability with two decoupled length scales. The spacing between fingers is determined by the P\'eclet number (ratio between advection and diffusion).
A. P. Aldushin   +14 more
core   +1 more source

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