Results 61 to 70 of about 199,455 (218)

Sudden swelling and redness of the toe

Clinical Case Reports, 2017
Key Clinical Message The presence of history of redness and swelling of toe in an infant without history of trauma is typical of hair threat tourniquet syndrome. The treatment simply involves incision and removal of hair fibers.
Vera Tengattini, Michela Magnano, Annalisa Patrizi, Iria Neri   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Change in the repair cycle of excavator fingers

Горное оборудование и электромеханика
The volumes of mined coal are affected by both the amount mining equipment (distribution by excavator-truck complex) and reliability associated with the smooth operation the open pit.
Levashova E.E.
doaj   +1 more source

Coxins interfalangeanos sobre paquidermodactilia Interphalangeal pads on pachydermodactyly

Anais Brasileiros de Dermatologia, 2004
Coxins interfalangeanos são nodulações ceratósicas, de limites precisos, com aproximadamente um centímetro de diâmetro, geralmente sobre as articulações interfalangenas das mãos.
José Marcos Pereira, Fernanda Corrêa Netto Pereira, Vivian Corrêa Netto Pereira   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The role of finger kinematics in the acquisition of number meaning in kindergarten: a pilot study

Frontiers in Education
Several studies have shown that the acquisition of number meaning is related to finger motor representations. However, no study has tried to distinguish the respective roles of fingers representation and finger kinematics in this effect.
Christel Bidet-Ildei, Christel Bidet-Ildei, Capucine Vilain, Sabine Fevin, Victor Francisco, Victor Francisco, Victor Francisco, Nicolas Vibert   +7 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Correlación entre dimensión vertical oclusal y longitud de los dedos de la mano en una población tumbesina adulta

Revista Facultad de Odontología Universidad de Antioquia
Introduction: In oral rehabilitation, multiple methods have been described to obtain the Vertical Occlusal Dimension (VOD), some based on aesthetics, others using functional, cephalometric, anthropometric, and facial craniometric approaches; but despite ...
Diana Katherin González-Orellana, Alfredo Carlos Manuel Rendón-Alvarado   +1 more
doaj   +1 more source