Results 91 to 100 of about 1,040,523 (340)
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Weeding... It Isn\u27t Just For Gardens [PDF]
Sorry, I haven’t posted in a while; I’ve been holding out until I got to the finishing stages of the Collection Development project. Yes, that’s right, for the past couple of weeks, when I was pacing up and down the stacks on the second floor, I was not ...
Farias, Jake A.
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Forty ewes (31.725±1.44 kg initial LW) were used to evaluate the effects of clinoptilolite (ZEOL) supplementation (0, 1, 2, and 3%, DM basis of diet) as substitute of soybean meal (SBM) in a finishing corn-based diet on growth performance, dietary ...
Alfredo Estrada-Angulo +8 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Young Black America Part Two: College Entry and Completion [PDF]
As documented in part one of this series, the high school completion rate of blacks is currently at the highest it has ever been. This second installment turns to college entry and completion.
Cherrie Bucknor
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Faba beans in diets for growing-finishing pigs [PDF]
Two experiments were carried out to study the effects of using the new faba bean (Vicia faba L.) cultivar Kontu as a domestic protein source for growing-finishing pigs.In Experiment 1,120 pigs were used with a body weight (BW)of 25–110 kg to study the ...
Alaviuhkola, Timo +3 more
core
Fostering Chinese firms through entrepreneurship, globalisation and international finance [PDF]
The success of ventures that have pursued non traditional marketing approaches may be attributed to a range of forward thinking practices which it is argued here, should be the starting and finishing points for Chinese companies.
Ardley, Barry +2 more
core +1 more source

