Results 91 to 100 of about 796,554 (292)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Converting Operations Impact on Tissue Paper Product Properties – A Review

open access: yesBioResources, 2023
Tissue paper is deep-rooted in our daily life because of its different types of products that allow various applications. Tissue paper is a low grammage paper that is mainly characterized by softness, tensile strength, liquid absorption, and elasticity ...
Joana Costa Vieira   +2 more
doaj  

Latino Youth Finishing College: The Role of Selective Pathways [PDF]

open access: yes, 2004
Assesses the dimensions of the gap in bachelor degree completions between Latinos and whites and some factors that contribute to it. Focuses on the differing fates of young people who graduate from high school with similar levels of academic ...
Richard Fry
core  

Fostering Chinese firms through entrepreneurship, globalisation and international finance [PDF]

open access: yes, 2012
The success of ventures that have pursued non traditional marketing approaches may be attributed to a range of forward thinking practices which it is argued here, should be the starting and finishing points for Chinese companies.
Ardley, Barry   +2 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

A novel eccentric lapping machine for finishing advanced ceramic balls [PDF]

open access: yes, 2001
Advanced ceramic balls are used extensively in hybrid precision ball bearings and show advantages in high speed, high temperature, high load and hostile environment.
Hadfield, M, Kang, J
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Putting it together and finishing the hat? Deconstructing the art of making art [PDF]

open access: yes, 2009
Contemporary Theatre Review is one of the leading peer-reviewed academic journals in the field of theatre studies. This special issue, ‘The Broadway Musical: New Approaches’, was put together by contributing editors Dominic Symonds and Dan Rebellato ...
Symonds, Dominic
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

ECONOMICS OF VARIABLE SWINE GROWTH [PDF]

open access: yes
This paper addresses the economic impacts of swine growth variability. Different economic penalties are determined to be associated with over-finishing versus under-finishing an animal.
Hoag, Dana L.   +2 more
core   +1 more source

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