Results 81 to 90 of about 1,040,523 (340)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Dyeing wool fabrics with specialized dyes and their mixtures using supercritical CO2

Scientific Reports
Wool has been colored in supercritical carbon dioxide in a few trials, yielding only a small spectrum of colors, mostly orange and yellow, with minimal research on alternative color combinations.
Hanan Elsisi, Tarek Abou Elmaaty, Elham Negm, Shahinaz Abouelenin   +3 more
doaj   +1 more source

Assessing Intestinal Health in Pigs: Recognizing Unaddressed Areas and Prospective Research Avenues

Veterinary Sciences
Gut health is crucial for pigs because it affects nutrient absorption, immune function, and growth performance. However, its definition remains unclear, particularly regarding measurable responses in scientific studies.
Marina Patricia Walter, Gabriela Miotto Galli, Alicia Zem Fraga, Aires Santos Silva, Júlio César Vieira Furtado, Pedro João Viera Ascari, Ines Andretta   +6 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Glimpse into reports on abrasive machining (Group G) during CIRP 2024 General Assembly

Jin'gangshi yu moliao moju gongcheng
To promote the international cutting-edge technical exchange in the field of abrasives, the Group G (abrasive processing) papers in the 2024 CIRP Annals – Manufacturing Technology journal have been specially selected for introduction. A total of 9 papers
Jiang GUO, Rongyan SUN, Zili ZHANG
doaj   +1 more source

Finishing pigs: conversion is more than respecting the standards [PDF]

, 2002
Food scares, mainly BSE and antibiotics, have sharpened consumers concerns about food safety and quality and have increased public attention on agricultural production and food processing. The demand for organic food has increased drastically in the year
Häring, A.M., Klumpp, C.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

MODELS OF OIL WOOD COATING MATERIALS SELECTION ACCORDING TO TECHNOLOGICAL, OPERATIONAL, ECOLOGICAL AND ECONOMIC CRITERIA [PDF]

Pro Ligno, 2014
This article presents the use of system analysis methodology and Graph Theory for validation of the relationships among descriptive factors, which impact the selection of oil materials for wood finishing. Matrix analysis was used to determine the results
Larysa YAREMCHUK, Tetyana OLYANYSHYN, Volodymyr MAKSYMIV, Liliya HOGABOAM   +3 more
doaj  

Effects of different backgrounding supplementation on performance and rumen morphometrics of Nellore bulls finished on tropical pasture [PDF]

Revista Brasileira de Zootecnia
This study aimed to evaluate the effects of backgrounding supplementation, by increasing the levels of energy-protein supplements during the growing phase on the performance and rumen morphometrics of Nellore bulls intensively finished on pasture. Ninety-
Jéssica Geralda Ferracini, Daniel Polli, Mariana Bassanezi Gasparim, Luanda Torquato Feba, Rodrigo José de Oliveira, Ariany Faria de Toledo, Danilo Domingues Millen   +6 more
doaj   +1 more source

A novel eccentric lapping machine for finishing advanced ceramic balls [PDF]

, 2001
Advanced ceramic balls are used extensively in hybrid precision ball bearings and show advantages in high speed, high temperature, high load and hostile environment.
Hadfield, M, Kang, J
core   +1 more source