Results 271 to 280 of about 15,309,834 (359)

A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves

open access: yesAdvanced Healthcare Materials, EarlyView.
Passive epicardial sleeves are evaluated in 3D in‐silico heart models to reveal how sleeve geometry, stiffness, anisotropy, and metamaterial architecture influence cardiac mechanics after myocardial infarction. A continuum‐to‐auxetic design exploration shows that region‐specific mechanical engagement can reduce infarct bulging and modulate torsional ...
Vahid Naeini   +8 more
wiley   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Distalization of the mandibular first molar with clear aligners: a 3D finite element study. [PDF]

open access: yesFront Bioeng Biotechnol
Kang F   +8 more
europepmc   +1 more source

An Ultra‐Flexible Neural Electrode with Bioelectromechanical Compatibility and Brain Micromotion Detection

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy