Results 101 to 110 of about 1,300,417 (304)

The Forgotten Campaign: Newfoundland at Gallipoli [PDF]

, 2018
Gallipoli has no place in the collective memory of most Canadians and even among Newfoundlanders, Gallipoli has not garnered as much attention as the ill-fated attack at Beaumont Hamel.
Cook, Tim, Humphries, Mark Osborne
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

The significance of pyrogenic polycyclic aromatic hydrocarbons in Borneo peat core for the reconstruction of fire history. [PDF]

PLoS One, 2021
Kong SR, Yamamoto M, Shaari H, Hayashi R, Seki O, Mohd Tahir N, Fadzil MF, Sulaiman A.   +7 more
europepmc   +1 more source

The early years of Sequoia and Kings Canyon Science: Building a research program [PDF]

, 2020
This paper provides a history of the development of the scientific research program at Sequoia and Kings Canyon National Parks (SEKI) during the period 1968–1994 from the perspective of one of the scientists involved.
Parsons, David J.
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Fire history from lake sediments

, 2014
Power point slides that illustrates the the conceptual model of how fires are reflected in lake sediments, as implmented in the CharSim model (Higuera et al. 2007, Quaternary Science Reviews).
openaire   +2 more sources

Fire history and weather interact to determine extent and synchrony of mast-seeding in rhizomatous scrub oaks of Florida. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2021
Pesendorfer MB, Bowman R, Gratzer G, Pruett S, Tringali A, Fitzpatrick JW.   +5 more
europepmc   +1 more source

Species and canopy cover map development using Landsat Enhanced Thematic Mapper imagery for Grand Canyon National Park [PDF]

, 2002
Overstory vegetation maps of species and canopy cover were developed from Landsat 7 Thematic Enhanced Thematic Mapper satellite imagery. Ecosystem Monitoring plot data, collected during the 1997-2001 field seasons, were used as training sites for the ...
Crouse, Joseph E., Fule, Peter Z.
core