Results 91 to 100 of about 12,105 (264)
Advanced Science, EarlyView.In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
Response to: Problems and promises of savanna fire regime change. [PDF]
Nat Commun, 2021 Lipsett-Moore GJ, Wolff NH, Game ET.
europepmc +1 more source
Restoring fire regimes through rewilding
Current BiologyAccelerating anthropogenic changes to climate and landscapes have degraded ecosystems globally; these include changes to naturally occurring disturbances, such as fires. Rewilding — the restoration of ecological processes to yield complex and resilient ecosystems — is a proposed strategy to maintain biodiversity in increasingly novel systems.
Plumanns-Pouton, Ella +7 more
openaire +2 more sources
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Frontiers in Ecology and EvolutionFire is the largest natural disturbance factor in the boreal forest and plays a critical role in the composition, structure, and succession of stands and landscapes.
Nickolas F. Lake +3 more
doaj +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Ecological implications of forest fire in seasonally dry tropical forests: a systematic review
Geology, Ecology, and LandscapesGlobally, fire plays a vital role in shaping ecosystem patterns and processes. Both directly and indirectly, fire regimes influence the structure, composition, distribution of biota, nutrient dynamics, and ecosystem carbon.
Shovasish Karna +1 more
doaj +1 more source
A Three-Regime Theorem for Flow-Firing
The Electronic Journal of CombinatoricsGraphical chip-firing is a discrete dynamical system where chips are placed on the vertices of a graph and exchanged via simple firing moves. Recent work has sought to generalize chip-firing on graphs to higher dimensions, wherein graphs are replaced by cellular complexes and chip firing becomes flow-rerouting along the faces of the complex. Given such
Brauner, Sarah +4 more
openaire +3 more sources
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
A weather pattern responsible for increasing wildfires in the western United States
Environmental Research LettersThe western United States (U.S.) has been experiencing more severe wildfires, in part due to climate change, but the underlying synoptic patterns and their modulation in driving fire weather is unclear.
Wei Zhang +5 more
doaj +1 more source