Results 71 to 80 of about 10,045,153 (250)
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Determining and Analyzing Factors Affecting Fire Safety Based on Fire Risk Assessment Method for Engineering and providing Control Solutions: A Case Study in a Hospital [PDF]
بهداشت و ایمنی کارIntroduction: Fire safety in healthcare centers is crucial due to the limited evacuation capacity of the occupants and the necessity of not disrupting the operation in these centers.
Samaneh Salari +3 more
doaj
The provision of fire services in rural areas [PDF]
, 2005 Fire services have been neglected in discussions of public service provision in rural areas. The way in which they are provided has a broader significance in terms of current debates about risk management.
Grant, Wyn
core +1 more source
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
A Framework for Assessment of Intentional Fires
Muhandisī-i bihdāsht-i ḥirfah/ī, 2014 Background & Objectives : It is not possible to live without using fire. However, fire could destruct human properties in a short time. One of the most important types of fire is intentional fire.
Iraj Mohammadfam +2 more
doaj
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Hazardous Chemical Laboratory Fire Risk Assessment Based on ANP and 3D Risk Matrix
The laboratory is a high-risk place for scientific research and learning, and there are many risk factors and great potential for harm. Hazardous chemicals are important to consider and are the key objects to monitor in a laboratory.
Yu Cao +3 more
core +1 more source
Advanced Science, EarlyView.Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Fire Safety Assessment of Building-Integrated Photovoltaics (BIPVs)
Building-Integrated Photovoltaic (BIPV) systems, which seamlessly integrate solar photovoltaic components into building structures, have garnered widespread attention for their aesthetic appeal and energy efficiency.
Ping Fang +5 more
core +1 more source