Results 111 to 120 of about 104,905 (268)
Advanced Science, EarlyView.STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang +8 more
wiley +1 more source
IPAC Firefly Development Roadmap [PDF]
, 2016 The IPAC Firefly package has been developed in IRSA (NASA/IPAC Infrared Science Archive) in the last six years. It is a software package utilizing state-of-the-art AJAX technology to provide an interactive web user interface for astronomers.
Wu, Xiuqin +6 more
core
Advanced Science, EarlyView.IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng +7 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice
Advanced Science, EarlyView.In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu +15 more
wiley +1 more source
Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication
Advanced Science, EarlyView.NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan +7 more
wiley +1 more source
A New Modified Firefly Algorithm [PDF]
, 2016 Nature inspired meta-heuristic algorithms studies the emergent collective intelligence of groups of simple agents. Firefly Algorithm is one of the new such swarm-based metaheuristic algorithm inspired by the flashing behavior of fireflies.
Gupta, Medha, Gupta, Divya
core +1 more source
FireFly Dating: Bachelor End Project [PDF]
, 2020 The FireFly company was created on the idea of blind dating. Most dating apps need the user to have an extensive conversation through a chat box before settling for a date.
Geukes, C. (author) +4 more
core
InsectsPygoluciola Wittmer 1939 is overviewed, with an expanded generic redescription comprising 28 species, including 6 new species from China, described from features of males, associated females, and larvae.
Xinhua Fu, Lesley Ballantyne
doaj +1 more source
Advanced Science, EarlyView.Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source