Results 81 to 90 of about 162,542 (259)

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Forestry research to support the transition towards a bio-based economy

Annals of Silvicultural Research, 2015
This special issue is dedicated to the celebration of the 92nd anniversary of the Forestry Research Centre of the Italian Agricultural Research Council.
Piermaria Corona
doaj   +1 more source

Da Firenze capitale alla “questione di Firenze”: imprenditori, affaristi e politici

, 2016
Alla Convenzione di settembre (1864) Firenze reagì con distacco e grande perplessità, ma i moderati toscani, uno dei gruppi più potenti del ceto dirigente italiano, compresero subito che l’ampliamento urbanistico della città e i relativi affari erano
MANETTI, DANIELA
core  

Translational development of crisugabalin for neuropathic pain

British Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João, Jilly Octoria Tagore Chan, Luísa Mendes Araújo, André Batista João, Raquel Mattos Filgueiras, Paulo César Ragazzo   +5 more
wiley   +1 more source

«Sulle sofferenze e sui danni subiti in questa guerra». Due memoriali dall’Archivio storico della Comunità ebraica di Firenze [PDF]

, 2011
Le persecuzioni antiebraiche a Firenze dopo l’8 settembre 1943 furono par- ticolarmente cruente. Malgrado l’efficacia e l’estensione di una rete protettiva di aiuti, la convinta collaborazione delle istituzioni locali della Repubblica Sociale Italiana ...
Baiardi, Marta
core   +1 more source

Emission Reduction Targets Between Strategy and Executive Compensation: Evidence on Symbolic and Substantive Adoption From German Listed Firms

Business Strategy and the Environment, EarlyView.
ABSTRACT Firms increasingly commit to climate targets yet doubts remain about whether such pledges translate into substantive corporate governance or remain symbolic. The study examines how emission reduction targets (ERTs) in sustainability strategies are reflected in compensation among German listed firms.
Victoria Fohrer, Anna‐Sofia Grabowski
wiley   +1 more source

Lucilla Conigliello, Chiara Melacca (ed.), Il '68 dei professori. L'Associazione Nazionale Docenti Universitari, Giorgio Spini e la riforma dell'Università, Firenze, Firenze University Press, 2018

Rivista di Storia dell'Educazione, 2019
Review: Lucilla Conigliello e Chiara Melacca, Il 68' dei professori. L'Associazione Nazionale Docenti Universitari, Giorgio Spini e la riforma dell'Università, Firenze, Firenze University Press, 2018, pp ...
Carmen Betti
doaj  

Martina Romanelli, “Ancor che tristo ha suoi diletti il vero”. Una lettura di Zibaldone 2999, Firenze, Società editrice fiorentina, 2018, pp. 212 [PDF]

, 2018
This review of “Ancor che tristo ha suoi diletti il vero”, an interpretation of Zibaldone 2999 (SEF, 2018) by Martina Romanelli focuses on an observation made on 21 July 1823 concerning late 16th century theatre.
Rekut-Liberatore, Oleksandra; Università degli Studi di Firenze
core   +1 more source

Rewiring the Circular Economy Through AI‐Informed Pathways: Structural and Distributional Drivers of Environmental Outcomes in the European Union

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates the structural and distributional factors that influence environmental performance in 27 European Union (EU) countries from 2010 to 2021, focusing especially on circular economy (CE) measures and the increasing use of artificial intelligence (AI)‐based analytical tools.
Cosimo Magazzino, Fabio Anobile, Luca Esposito, Tulia Gattone   +3 more
wiley   +1 more source