Results 211 to 220 of about 164,418 (289)

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Fire at the boundary: Airborne toxic metals from the 2025 Los Angeles urban firestorm. [PDF]

Sci Adv
Baliaka HD, Ward RX, Raffuse SM, Ries B, Cui Y, Wu D, Liu R, Barut C, Hasheminassab S, Tissot FLH, Russell AG, Seinfeld JH, Flagan RC, Bahreini R, Wennberg PO, Ng NL.   +15 more
europepmc   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Waste fire surveillance: A case study using remote sensing data and IoT ground sensing for monitoring fires at waste management sites. [PDF]

Waste Manag
Woldeyohannes T, Lin Y, Zhang X, Doyle J, Eggers M, Liu Z, Hridoy AE, Bimaghra EM, Bizure T, Mirka B, James L, Hoover J.   +11 more
europepmc   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

Drought and overwintering fires drive consecutive large fire seasons in boreal North America

Scholten R, Chen Y, Field R, Kim J, Burrows W, Carr R, Liu T, McCabe T, Morton D, Rigden A, Rogers B, Randerson J.   +11 more
europepmc   +1 more source

Climate-driven upward spread of forest fires in European mountain regions. [PDF]

Nat Commun
Beloiu M, Loeillot T, Griess VC, Poursanidis D, Petibon F.   +4 more
europepmc   +1 more source

Fire‐Safe Hierarchical Solid Polymer Electrolytes Enabled by Dual‐Functional Microcapsules for Lithium Metal Batteries

Advanced Science, EarlyView.
Dual‐functional fire‐safe microcapsules are integrated into hierarchical solid polymer electrolytes to provide sequential protection against thermal abuse. The ammonium hydrogen phytate‐modified shell forms a protective char barrier, while the thermally triggered release of perfluoro(2‐methyl‐3‐pentanone) actively suppresses combustion, enabling safer ...
Ziqi Huang, Jiuqing Gui, Qiaoying Cao, Yong Xiao, Hang Hu, Yeru Liang   +5 more
wiley   +1 more source

Geographical characteristics and other factors associated with alcohol-related fatal fires in Ireland 2014 - 2021. [PDF]

HRB Open Res
Doyle A, Stevely AK, Lyons S, McBride J, Riordan F, Holmes J.   +5 more
europepmc   +1 more source

Excitation‐Selective Hydrochromic Upconversion in Zero‐Dimensional Metal Halides

Advanced Science, EarlyView.
Excitation wavelength dictates whether moisture speaks. In zero‐dimensional metal halides, the same humidity leaves the upconversion emission unchanged under 980 nm excitation yet triggers a distinct green‐to‐red shift under 1550 nm. This excitation‐selective hydrochromism, governed by the absorption at each wavelength, enables stimulus‐dependent ...
Joo Hyeong Han, Jeong Min Seo, Sung Woo Jang, Yong Min Park, San Ha Choi, Ji Hyeon Cha, Won Bin Im   +6 more
wiley   +1 more source