Results 191 to 200 of about 1,340,805 (345)

<i>N</i>,<i>N</i>-Diisopropyltryptamine and diptogenia: proposed mechanisms for a frequency-selective pitch-distorting psychedelic. [PDF]

Brain Commun
Hurst A, Bajo VM.
europepmc   +1 more source

NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex.

Neuron, 2013
Min Wang, Yang Yang, Ching-Jung Wang, Nao J. Gamo, Lu E. Jin, J. Mazer, J. Morrison, Xiao-Jing Wang, A. Arnsten   +8 more
semanticscholar   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Contribution of proprioceptors in the mesencephalic trigeminal nucleus and their surrounding astrocytes to acidic saline-induced chronic jaw muscle pain in rodents. [PDF]

Front Cell Neurosci
Yamada M, Verdier D, Kolta A.
europepmc   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

An updated view on lagging strand DNA replication: implications for the replication stress response. [PDF]

Cell Cycle
Martín-Rufo R, Lecona E.
europepmc   +1 more source

Hawaii Ocean Time-series Program Data Report 1, 1988-1989 [PDF]

, 1990
Chiswell, Stephen, Firing, Eric, Karl, David, Lukas, Roger, Winn, Christopher   +4 more
core  

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

α-Synuclein oligomers slow down action potential firing and enhance dopamine release by increasing Cav2.2 currents in midbrain dopaminergic neurons. [PDF]

J Physiol
Tomagra G, Battaglia A, Franchino C, Bonzano S, Picollo F, Chiantia G, de Iure A, Calabresi P, Picconi B, Carbone E, De Marchis S, Marcantoni A, Carabelli V.   +12 more
europepmc   +1 more source

Stimulation of the Subthalamic Nucleus Changes the Firing Pattern of Pallidal Neurons

Journal of Neuroscience, 2003
T. Hashimoto, Christopher M. Elder, M. Okun, S. K. Patrick, J. Vitek   +4 more
semanticscholar   +1 more source