WS2‐based in‐memory sensing reservoir computing integrates sensing, memory, and computation in one compact device. It achieves ∼94% N‐MNIST, ∼93% eye motion perception, and ∼89% speech recognition with ultra‐low energy (∼25.5 fJ/spike). The system shows stability at 95% humidity, endurance over 1.5M cycles, and supports synaptic plasticity, enabling ...
Dayanand Kumar +9 more
wiley +1 more source
How the dynamic interplay of cortico-basal ganglia-thalamic pathways shapes the time course of deliberation and commitment. [PDF]
Yu Z, Verstynen T, Rubin JE.
europepmc +1 more source
This research demonstrates that incorporating 10 wt.% NASICON‐type Na3Zr2Si2PO12 into Na3SbS4 sulfide electrolytes mitigates interfacial instability and structural defects. The resulting composite enhances ionic conductivity to 3.97 * 10−4 S cm−1 and reduces activation energy.
Celastin Bebina Thairiyarayar +4 more
wiley +1 more source
Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness. [PDF]
Yang S +12 more
europepmc +1 more source
Localizable Fluorescent Metal Ion Indicators With Tunable Colors
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self‐labeling proteins yields bright, color‐tunable potassium probes that permit wash‐free live‐cell imaging, revealing dynamic potassium efflux in stimulated neurons.
Ming‐Ming Wang +3 more
wiley +1 more source
Alzheimer's disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits. [PDF]
Ellingford R +21 more
europepmc +1 more source
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
Dynamic changes in excitability and viability of sporadic and <i>SOD1</i>-related amyotrophic lateral sclerosis iPSC-derived motor neurons. [PDF]
Qi M +5 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease. [PDF]
Ritoux A +6 more
europepmc +1 more source

