Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Praxeology and the firm: a contribution to the Austrian redefinition of the economic organization problem [PDF]
The aim of this paper is to syntetize theory of entrepreneurship of the Austrian School of economics with the contractual theory of the firm. Transaction cost theory of Ronald Coase and his followers holds that the firm is the organization with dominant ...
Janković Ivan
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PENGARUH STRUKTUR KEPEMILIKAN DARI CORPORATE GOVERNANCE PADA BADAN USAHA PUBLIK YANG TERDIVERSIFIKASI DAN TIDAK TERDIVERSIFIKASI DALAM HUBUNGANNYA DENGAN LAYANAN BAGI PIHAK INTERNAL DAN EKSTERNAL BADAN USAHA [PDF]
The stakeholders of the firm have the same objective to the survival of the firm. In order to survive, the firm can diversify its line of business.
Loebiantoro, Ika Yanuarti +1 more
core
Corporate governance structure and firm performance : empirical evidence from Brusa Malaysia, Kuala Lumper [PDF]
The issue of corporate governance has been emerging as important phenomena that has been searched extensively both in developed countries due to its strategic impact on the monitoring of management activities and firms’ performance.
Ali Ahmed, Huson Joher, Ali, Mohd
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Networking perspective of coordinating innovative actions [PDF]
Seeking the most favorable conditions for innovative activity, the article depicts the results of research on innovativeness in the context of coordination.
Teresa Bal-Woźniak
doaj
Foreign direct investments (FDI) have a major role in the British economy. In the political, cultural, social and economic context of the United Kingdom, the settlement of foreign firms also has major geopolitical implications on different scales ...
Mark Bailoni
doaj +1 more source
Firm Performance, Worker Commitment and Loyalty [PDF]
Using matched employer-employee level data drawn from the UK Workplace and Employee Relations Survey, we explore the influence of worker commitment and loyalty on firm level labour productivity and financial performance.
Brown, S., McNabb, R., Taylor, K.
core

