Results 71 to 80 of about 1,403,813 (315)

Like milk or wine: Does firm performance improve with age? [PDF]

open access: yes
Our empirical literature review shows that little is known about how firm performance changes with age, presumably because of the paucity of data on firm age.
Agustí Segarra   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A multistate demographic model for firms in the province of Gelderland [PDF]

open access: yes
In the last two decades researchers from various disciplines have made attempts to model and estimate developments in the size and structure of the population of firms.
Corina Huisman, Leo Van Wissen
core  

One-Fifth of Nonelderly Californians Do Not Have Access to Job-Based Health Insurance Coverage [PDF]

open access: yes, 2010
Examines access to employer-based coverage among children and nonelderly adults age 64 and under, insurance status, and other sources of coverage, including Medi-Cal and family coverage, by income, firm size, citizenship, race/ethnicity, and ...
Livier Cabezas, Shana Alex Lavarreda
core  

Investigating the Exponential Age Distribution of Firms [PDF]

open access: yesSSRN Electronic Journal, 2010
Abstract While several plots of the aggregate age distribution suggest that firm age is exponentially distributed, we find some departures from the exponential benchmark. At the lower tail, we find that very young establishments are more numerous than expected, but they face high exit hazards.
openaire   +8 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Product innovation and employees’ slack time. The moderating role of firm age & size

open access: yesJournal of Innovation & Knowledge, 2020
A growing mass of study has underscored that slack resources are fundamental for innovation. However, empirical research has generated inconclusive findings that have invigorated an ongoing scholarly discussion about which sorts of slack resources are ...
Stephen Kehinde Medase
doaj   +1 more source

Selection and Firm Survival: Evidence from the Shipbuilding Industry, 1825-1914 [PDF]

open access: yes
Several theories of firm performance can explain the well-known observation that survival is positively related to age. However, a more mundane explanation – selection bias driven by variations in firm quality – may also underlie the phenomenon.
Peter Thompson
core  

Small firms, borrowing constraints, and reputation [PDF]

open access: yes, 1995
This paper presents a simple model relating firm age with firm size and access to credit markets. Lending to new firms is risky because lenders have had no time to accumulate observations about them.
Martinelli, César
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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