Results 91 to 100 of about 1,523,391 (358)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Innovation and Corporate Dynamics: A Theoretical Framework [PDF]

open access: yes
We provide a detailed analysis of a model of innovation and corporate dy- namics that encompasses the Gibrat’s Law of Proportionate Effect and the Simon growth process as particular instances. The predictions of the model are derived in terms of (i) firm
Fabio Pammolli   +2 more
core  

Cyclicality and Firm-size in Private Firm Defaults [PDF]

open access: yesInternational Journal of Central Banking, 2017
The Basel II/III and CRD-IV Accords reduce capital charges on bank loans to smaller firms by assuming that the default probabilities of smaller firms are less sensitive to macroeconomic cycles. We test this assumption in a default intensity framework using a large sample of bank loans to private Danish firms. We find that controlling only for size, the
Jensen, T., Lando, D., Medhat, M.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Firm size and the extensive margin

open access: yesEconomic and Business Review, 2011
<p>In this paper we rely on firm-product-destination level data to analyze Hungarian trade expansion between 1992 and 2003. We decompose trade growth to the number of firms, the number of markets and products per firm, and analyze these dimensions ...
László Halpern, Balázs Muraközy
doaj  

DETERMINANTS OF FIRM VALUE FACTORS OF INDONESIAN SHARIA STOCKS LISTED ON THE INDONESIAN STOCK EXCHANGE

open access: yesI-Finance
The purpose of this study was to determine and analyze the effect of profitability, company size and dividend policy on firm value. The population and sample are all companies that have sharia shares listed on the Indonesia Stock Exchange as many as 20 ...
Maren Alisa   +2 more
doaj   +1 more source

PENGARUH STRUKTUR KEPEMILIKAN DARI CORPORATE GOVERNANCE PADA BADAN USAHA PUBLIK YANG TERDIVERSIFIKASI DAN TIDAK TERDIVERSIFIKASI DALAM HUBUNGANNYA DENGAN LAYANAN BAGI PIHAK INTERNAL DAN EKSTERNAL BADAN USAHA [PDF]

open access: yes, 2005
The stakeholders of the firm have the same objective to the survival of the firm. In order to survive, the firm can diversify its line of business.
Loebiantoro, Ika Yanuarti   +1 more
core  

Firm size – firm growth relationship during economic crises

open access: yesEkonomska misao i praksa = Economic Thought and Practice, 2020
Velika recesija 2008. godine snažno je pogodila poduzetnički sektor diljem svijeta. Razumijevanje načina kako poduzeća reagiraju u vrijeme globalne krize ključno je za formuliranje adekvatnih politika i mjera za ublažavanje krize. Koristeći uzorak od 7.563 hrvatskih poduzeća u prerađivačkoj industriji i ugostiteljstvu koje su preživjele šestogodišnje ...
Perić, Marko   +2 more
openaire   +4 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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