Results 91 to 100 of about 10,834 (260)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Corporate Valuation and Governance: Evidence from Colombia [PDF]

open access: yes
This paper examines for the first time the association of different ownership and control measures and separation ratios with a firm`s value and performance for 108 non-financial firms that traded their stock during the period 1998 to 2002.
Carlos Pombo, Luis H. Gutiérrez
core  

Corporate ownership and market valuation in South Africa: uncovering the effects of shareholdings by different groups of corporate insiders and outsiders

open access: yes, 2013
This paper examines the connection between shareholdings by different groups of corporate officers (insiders and outsiders), and market valuation in South Africa. Specifically, and distinctively, we examine the effect of shareholdings by employees, chief
Ntim, Collins G.
core   +1 more source

Stock Valuation and Investor Expectations

open access: yesEncyclopedia
Stock valuation models can be used to guide the investment decisions of institutions or individuals. In the traditional approach, the investor will use a valuation model to calculate a stock’s intrinsic value as a function of the estimated future cash ...
Morris G. Danielson
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Corporate Governance and Firm Valuation in Colombia [PDF]

open access: yes
This paper studies the separation of ownership and control of 108 listed companies in Colombia from 1996 to 2002, finding that voting rights are greater than cash flow rights because of indirect ownership across firms.
Carlos Pombo, Luis H. Gutiérrez
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

CHANGE AND FIRM VALUATION IN U.S. FOOD RETAILING AND MANUFACTURING

open access: yes
The competitive environment in the agri-food sector is evolving as the food manufacturing and retailing industries become more concentrated. Evolving industry structure and new firm investment portend changes in future firm competitiveness and ...
Bjornson, Bruce, Kaufman, Phillip R.
core  

Diversification in Firm Valuation: A Multivariate Copula Approach [PDF]

open access: yes
We introduce a new discounted cash flow model which adopts the diversification effect of multi-business firms. We face two challenges: One is examining how different diversification extents can affect the firm value due to risk reduction, and the other ...
Nicolas Heinrichs   +2 more
core  

Value drivers and target valuation [PDF]

open access: yes, 2008
Chapter objectives: - Provides a link between growth and shareholder value - Highlights the role of three value drivers in value creation - Introduction to alternate valuation frameworks like free cash flow to firm, adjusted present value, capital cash ...
Vishwanath, S. R.   +1 more
core  

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