Results 41 to 50 of about 876,779 (294)

Nonprofits and Pass-Throughs: Performance Comparison

open access: yesInternational Journal of Financial Studies, 2021
This paper’s purpose is to compare nonprofits with pass-throughs in terms of valuation, leverage, and growth. To achieve this purpose, we use the Capital Structure Model.
Robert Hull, Shane Van Dalsem
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Board Independence, Financial Performance, and Share Price Dynamics: Evidence from Nigerian Consumer Goods Firms

open access: yesReviews of Management Sciences
Purpose This study examines the determinants of share prices among Nigerian consumer goods firms, focusing on firm-specific characteristics, capital structure, and the moderating effect of board independence.
Emmanuel Imuede Oyasor
doaj   +1 more source

The relationship between human capital and firm value: Evidence from Indian firms

open access: yesCogent Economics & Finance, 2021
The purpose of this paper is to investigate whether human capital affects firm value by following a positive methodological approach. According to the classical theory of economic growth, the output of a country depends on its human and physical capital.
Garima Sisodia   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The valuation of asset management firms [PDF]

open access: yesCorporate Ownership and Control, 2019
After reviewing the main valuation frameworks of asset management firms, we ran empirical research on 50 listed US and European asset management firms in the 2008-2017 period. Our results find that such firms are characterized by a high EBIT and earnings margin, respectively equal, on average, to 28% and 17% of revenues, represented by fees.
Bigelli, Marco, Manuzzi, Fabio
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Analysis of Corporate Bond Valuation under an Infinite Dimensional Compound Poisson Framework

open access: yesAbstract and Applied Analysis, 2014
This paper analyzes the firm bond valuation and credit spread with an endogenous model for the pure default and callable default corporate bond. Regarding the stochastic instantaneous forward rates and the firm value as an infinite dimensional Poisson ...
Sheng Fan
doaj   +1 more source

Firm valuation and accounting numbers [PDF]

open access: yesEstudos de Gestão - Portuguese Journal of Management Studies, 2000
Accounting information on earnings and book values is commonly used to help value a firm. The errors that arise from the use of these data stem from the fact that accounting depreciation is not generally equal to expected economic depreciation and that earnings are liable to random shocks.
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy