Results 51 to 60 of about 55,126 (291)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Multivariate Padé Approximation for Solving Nonlinear Partial Differential Equations of Fractional Order

open access: yesAbstract and Applied Analysis, 2013
Two tecHniques were implemented, the Adomian decomposition method (ADM) and multivariate Padé approximation (MPA), for solving nonlinear partial differential equations of fractional order. The fractional derivatives are described in Caputo sense.
Veyis Turut, Nuran Güzel
doaj   +1 more source

Variational first-order partial differential equations

open access: yesJournal of Differential Equations, 2003
Let \(\pi_1: J^1 Y\to X\) be the jet prolongation of a fibered manifold \(\pi: Y\to X\). Denoting \((x^i, y^\sigma, y^\sigma_j)\) the local fibered coordinates and \(\omega^\sigma= dy^\sigma- \sum y^\sigma_j dx^j\) the contact forms on \(J^1Y\), the article is devoted to formal algebraic properties of the multiple variational integral \(\int\rho ...
Haková, Alžběta, Krupková, Olga
openaire   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Exact solutions of fractional mBBM equation and coupled system of fractional Boussinesq-Burgers

open access: yesResults in Physics, 2018
The new exact solutions of nonlinear fractional partial differential equations (FPDEs) are established by adopting first integral method (FIM). The Riemann-Liouville (R-L) derivative and the local conformable derivative definitions are used to deal with ...
Shumaila Javeed   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Absolutely stable difference scheme for the delay partial differential equation with involution and Robin boundary condition

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This paper examines the initial value problem for a third-order delay partial differential equation with involution and Robin boundary condition. We construct a first-order accurate difference scheme to obtain the numerical solution for this equation ...
A. Ashyralyev, S. Ibrahim, E. Hincal
doaj   +1 more source

The First Integral Method to the Nonlinear Schrodinger Equations in Higher Dimensions

open access: yesAbstract and Applied Analysis, 2013
The first integral method introduced by Feng is adopted for solving some important nonlinear partial differential equations, including the (2 + 1)-dimensional hyperbolic nonlinear Schrodinger (HNLS) equation, the generalized nonlinear Schrodinger (GNLS ...
Shoukry Ibrahim Atia El-Ganaini
doaj   +1 more source

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