Results 111 to 120 of about 3,152,534 (307)

Markov Logic Based Inference Engine for CDSS [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2017
CDSS (Clinical Decision Support System) is typically a diagnostic application and a modern technology that can be employed to provide standardized and quality medical facilities to the medical patients especially when expert doctors are not available ...
IMRAN SARWAR BAJWA   +2 more
doaj  

Decomposition of a second-order linear time-varying differential system as the series connection of two first order commutative pairs

open access: yesOpen Mathematics, 2016
Necessary and sufficiently conditions are derived for the decomposition of a second order linear time- varying system into two cascade connected commutative first order linear time-varying subsystems. The explicit formulas describing these subsystems are
Koksal Mehmet Emir
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Improved Discretization Error Estimates for First-Order System Least Squares (FOSLS)

open access: yes, 2003
We study the discretization accuracy for first-order system least squares (FOSLS) applied to Poisson's equation as a model problem. The FOSLS formulation is based on an H elliptic bilinear form F .
Steve Mccormick   +3 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Comprehensive Examination: First-Order System Least Squares and Adaptive Mesh Refinement

open access: yes, 1997
We want to study the properties of the local first-order system least squares (FOSLS) functional. We believe that it can be used as a local a-posteriori error estimator and hence as an indicator where adaptive mesh refinement (AMR) makes sense.
Markus Berndt
core  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Div First-Order System LL * (FOSLL*) for Second-Order Elliptic Partial Differential Equations ∗

open access: yes, 2014
. The first-order system LL * (FOSLL*) approach for general second-order elliptic partial differential equations was proposed and analyzed in [10], in order to retain the full efficiency of the L2 norm first-order system least-squares (FOSLS) ap-proach ...
Rob Falgout, Shun Zhang, Zhiqiang Cai
core  

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