Results 81 to 90 of about 3,152,534 (307)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Big-bang bifurcations in a first order system with a relay
, 2011 In this work we describe the bifurcation scenario found in a general first order system when a relay based proportional control is considered. We show the existence of a big bang bifurcation causing the existence of an infinite number of period orbits ...
Granados, Albert, Fossas Colet, Enric
core +1 more source
Spreadsheets in Education, 2014 Motivated by the work of a spreadsheet solution of a system of ordinary differential equations (ODEs) using the fourth-order Runge-Kutta (RK4) method, a RK4 spreadsheet calculator for solving a system of two first-order ODEs was developed using VBA ...
Kim Gaik Tay +4 more
doaj
Chaos-Based Underwater Communication With Arbitrary Transducers and Bandwidth
Applied Sciences, 2018 In this work, an enhanced differential chaos shift keying (DCSK), based on a first order hybrid chaotic system, is being proposed for a high reliability underwater acoustic communication system.
Chao Bai +3 more
doaj +1 more source
Periodic solutions for first order differential systems
Applied Mathematics Letters, 2010 The paper presents some existence and uniqueness results for periodic systems of the form \[ {\mathbf x}' = G(t,{\mathbf x}), \qquad {\mathbf x} (0) = {\mathbf x} (2\pi), \] where \(G(t,{\mathbf x}) : \mathbb{R} \times \mathbb{R}^n \to \mathbb{R}^n\) is Lipschitz continuous, \(2\pi\)-periodic in \(t\), and \(\frac{\partial G(t,{\mathbf x})}{\partial ...
Ravi P. Agarwal, Jinhai Chen
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
First-order product-type systems of difference equations solvable in closed form
Electronic Journal of Differential Equations, 2015 We show that the first-order system of difference equations $$ z_{n+1}=\alpha z_n^aw_n^b,\quad w_{n+1}=\beta z_n^cw_n^d,\quad n\in\mathbb{N}_0, $$ where $a,b,c,d\in\mathbb{Z}$, $\alpha,\beta \in\mathbb{C}\setminus\{0\}$, $z_0, w_0\in\mathbb{C ...
Stevo Stevic
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Inverse Boundary Value Problem for a First Order System
, 2010 noneIn the two-dimensional case, we consider the problem of determining the potential A from the set of Cauchy data for the equation Pu=Du+Au=0.
Lai, Ru-Yu, 賴如育
core
Control System Design Based on a Universal First Order Model with Time Delays
Acta Polytechnica, 2001 An original modelling approach for SISO systems is presented, based on a first order model with more than one delay in its structure. By means of this model it is possible truly to hit off the properties of systems which are conventionally described by ...
T. Vyhlídal, P. Zítek
doaj