Results 71 to 80 of about 952,884 (290)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Elastic properties of superconducting MAX phases from first principles calculations

, 2010
Using first-principles density functional calculations, a systematic study on the elastic properties for all known superconducting MAX phases (Nb2SC, Nb2SnC, Nb2AsC, Nb2InC, Mo2GaC and Ti2InC) was performed. As a result, the optimized lattice parameters,
Akimitsu, Bai, Barsoum, Born, Bortolozo, Bortolozo, Bortolozo, Bouhemadou, Bray, Cover, Eklund, Haines, Hill, Isaev, Ivanovskii, Ivanovskii, Kanoun, Kanoun, Kresse, Kresse, Lofland, Luongo, Mazumdar, Perdew, Pugh, Ravindran, Reuss, Sakamaki, Shein, Shein, Shein, Shein, Sun, Toth, Tvergaard, Vinod, Voigt, Wang, Wu   +38 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Electric field gradients from first-principles and point-ion calculations

, 2001
Point-ion models have been extensively used to determine "hole numbers" at copper and oxygen sites in high-temperature superconducting cuprate compounds from measured nuclear quadrupole frequencies. The present study assesses the reliability of point-ion
Claxton, T. A., Meier, P. F., Stoll, E. P.   +2 more
core   +1 more source

Crystals from metallic clusters: A first-principles calculation [PDF]

Physical Review B, 1993
The interactions of the ``magic'' ${\mathrm{Al}}_{12}$Si clusters are studied by first-principles electron-structure calculations. It is shown that clusters arranged into the fcc lattice do not conserve their separated-cluster icosahedral structure but coalesce to form a close-packed metal.
Seitsonen, A. P., Puska, M. J., Alatalo, M., Nieminen, R. M., Milman, V., Payne, M. C.   +5 more
openaire   +3 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Lattice dynamics, elastic, magnetic, thermodynamic and thermoelectric properties of the two-dimensional semiconductors MPSe3 (M = Cd, Fe and NI): a first-principles study

Materials Research Express, 2022
Adopting Density Functional Theory (DFT) with Hubbard U correction implemented in Quantum Espresso, we have performed a comprehensive first-principles study of MPSe _3 (M = Cd. Fe and Ni) monolayers.
A A Musari, Peter Kratzer
doaj   +1 more source

First Principles Calculations of Ionic Vibrational Frequencies in PbMg1/3Nb2/3O3

, 2003
Lattice dynamics for several ordered supercells with composition PbMg1/3Nb2/3O (PMN) were calculated with first-principles frozen phonon methods. Nominal symmetries of the supercells studied are reduced by lattice instabilities.
Burton, E. P., Cockayne, E., Prosandeev, S. A.   +2 more
core   +1 more source

Characterization of platinum nitride from first-principles calculations [PDF]

Journal of Physics: Condensed Matter, 2009
We have performed a systematic study of the ground state properties of the zinc-blende, rock-salt, tetragonal, cuprite, fluorite and pyrite phases of platinum nitride by using the plane wave pseudopotential calculations within the density functional theory. The equilibrium structural parameters and bulk moduli are computed within both the local density
Yildiz, A., Akinci Ü., Gülseren O., Sökmen I.   +3 more
openaire   +6 more sources