Strong plasmon-molecule coupling at the nanoscale revealed by first-principles modeling
, 2019 Tuomas P. Rossi +3 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
, 2007 Electron neutrino has been the first neutral lepton to be foreseen and discovered last century. The un-ordered muon and its neutrino arose later by cosmic rays.
D'Armiento, D. +2 more
core
Infant Dietary Exposures to Sweetness and Fattiness Increase during the First Year of Life and Are Associated with Feeding Practices [PDF]
, 2016 Wen Lun Yuan +6 more
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
مفهوم العدالة وضوابطها عند المحدثين
گۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆ, 2013 يتناول هذا البحث دراسة شرط من شروط صحة الحديث النبوي ألاّ وهو شرط العدالة في رواة الحديث، فالعدالة شرط لقبول الرواية وصحتها عند جماهير أهل العلم بالحديث والفقه والأصول؛ لأنها ملكة عند المرء تحمله على ملازمة التقوى واجتناب المحظور، فمن لم يكن على هذه ...
First A. Al - Warmili
doaj
Association of phosphatase and tensin homolog low and phosphatidylinositol 3-kinase catalytic subunit alpha gene mutations on outcome in human epidermal growth factor receptor 2-positive metastatic breast cancer patients treated with first-line lapatinib plus paclitaxel or paclitaxel alone [PDF]
, 2014 Binghe Xu +9 more
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Cytomegalovirus serological screening at the first antenatal visit: A tertiary‐centre audit of general practitioner practices and maternal seroprevalence [PDF]
, 2023 Ignatius Rudd +2 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source