Results 191 to 200 of about 35,395,600 (301)

Razvod braka, Izbor iz bibliografije jugoslavenskih radova 1950.–1915. godine [PDF]

, 1976
Ruža First-Dilić
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Elevated Serum Interleukin 6 Is Associated With High Risk of First Non-bleeding Decompensation in Patients With Compensated Cirrhosis. [PDF]

In Vivo
Kita Y, Ikeda Y, Nago H, Yamaguchi M, Kato Y, Om R, Terai Y, Sato S, Murata A, Sato S, Shimada Y, Nagahara A, Genda T.   +12 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Early success of the COCOON trial: Preventing dermatologic adverse events in first-line EGFR-mutant NSCLC. [PDF]

Oncoscience
Tiwari B, Koirala A.
europepmc   +1 more source

First Impressions: LJ\u27s First Year Experience Survey [PDF]

, 2017
Dixon, Jennifer
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A country-wide survey of knowledge and practice regarding prevention, snake identification and pre-hospital management of children with snakebites amongst Public Health Midwives in Sri Lanka. [PDF]

PLoS Negl Trop Dis
Dayasiri K, Perera T, Gunarathna G, Ranasinghe A, Gawarammana I, Jayamanne S.   +5 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

ST-segment elevation in acute pericarditis and myocardial involvement: electrocardiographic and clinical profiling. [PDF]

Open Heart
Ceriani E, Berra S, Agozzino F, Ceriani M, Ghisolfi L, Moda F, Rubuano F, Sicignano LL, Gerardino L, Trotta L, Pancrazi M, De Carlini CC, Maestroni S, Cumetti D, Carrozzo L, Casarin F, Collini V, Imazio M, Brucato A.   +18 more
europepmc   +1 more source