Results 251 to 260 of about 49,815,865 (394)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Upper-limb range of motion in children with cerebral palsy treated with botulinum neurotoxin: a population-based cohort study. [PDF]

BMC Musculoskelet Disord
Hedberg-Graff J, Granström F, Arner M, Rodby-Bousquet E, Krumlinde-Sundholm L.   +4 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Review on international congress: XX CROMAR congress: Marketing in knowledge society and contemporary business reality [PDF]

Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2007
Ivana First
doaj  

Correction to "Evaluation of ImpENSA Technology-Enabled Behaviour Change Module Delivered to Healthcare Professionals in South Africa to Improve Micronutrient Nutrition During the First 1000 Days". [PDF]

Matern Child Nutr
europepmc   +1 more source

Biomedical and life science articles by female researchers spend longer under review. [PDF]

PLoS Biol
Alvarez-Ponce D, Batz G, Ramirez Torres L.   +2 more
europepmc   +1 more source

The FIRST Survey: Faint Images of the Radio Sky at twenty centimeters

, 1995
R. Becker, R. White, D. Helfand
semanticscholar   +1 more source

Scotland’s mental health first aid : young people : year 4 final report [PDF]

, 2020

core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

First Impressions: LJ\u27s First Year Experience Survey [PDF]

, 2017
Dixon, Jennifer
core   +1 more source