Results 91 to 100 of about 1,101,220 (313)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Knowledge, attitude, and practices of burn first aid and its preventive measures among undergraduate medical students of Umm Al-Qura University: A cross-sectional study [PDF]

, 2022
Omar Safran Alhothali, Reem Abdullah Alharthi, Ammar Safran Alhothali, Lujain Ahmad Alzahrani, Aroob Abdulhalim, Mohammed Amro Fouda, Fares Alaa Sultan, Alaa A Sultan   +7 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

An evaluation of the teen and Youth Mental Health First Aid training with a CALD focus: an uncontrolled pilot study with adolescents and adults in Australia

International Journal of Mental Health Systems, 2019
Background Australia is an ethnically diverse nation with one of the largest refugee resettlement programs worldwide. Evidence suggests that although the risk of developing mental disorders in culturally linguistically diverse (CALD) adolescents may be ...
Maria Gabriela Uribe Guajardo, Claire Kelly, Kathy Bond, Russell Thomson, Shameran Slewa-Younan   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Stroke Recognition for First Aid Providers: A Systematic Review and Meta-Analysis [PDF]

, 2020
Daniel Meyrán, Pascal Cassan, Bert Avau, Eunice M. Singletary, David Zideman   +4 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Exploring the mechanisms that underpin an effective community first aid response: a rapid realist review 

International Journal of First Aid Education
Background Community First Aid (CFA) interventions aim to improve the capacity of a community to effectively respond to urgent and emergency health needs, by providing training, education or response services.
Claire Maynard, Laura Sims, Matthew Booker   +2 more
doaj   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

First Aid in the Workplace: 10 Basics Everyone Should Know [PDF]

, 2005
Michele Ostrove
openalex   +1 more source