Results 171 to 180 of about 4,419,277 (309)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Bridging the Knowledge-Practice Gap in Cervical Spine Injury First Aid: A Cross-Sectional Study in Southern Saudi Arabia. [PDF]

Healthcare (Basel)
Khormi YH, Jareebi MA, Madkhali AY, Abu Alzawayid NAN, Muthaffar AH, Masri TA, Albarrati EM, Hakami MH, Ageeli SA, Alshahrani MS, Alzahrani RM, Tawashi FH, Hakami IA, Al Jowf GI, Algahtani FH.   +14 more
europepmc   +1 more source

Mutual Aid and Service Agreements: Wise Practices for First Nations Communities [PDF]

, 2017
Chrétien, Annette, McLean-Purdon, Erin, Murphy, Brenda, Pearce, Laurie   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Mental Health First Aid Training as a Wellness Initiative for First Year Medical Students. [PDF]

Adv Med Educ Pract
Thilges S, Goldhaber K, Shahid R.
europepmc   +1 more source

New legislation and guidance for first aid at work in Belgium [PDF]

, 2012
De Ridder, Maurits, Mpotos, Nicolas
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Assessment of Community Knowledge, Attitudes and Practices Regarding Burn Prevention and First Aid in Yemen: A Cross-Sectional Study. [PDF]

Int Wound J
Alsiaghi YA, Al-Sayaghi NY, Othman BM, Al-Ajaly MY, Altam A, Ghanem AM, ALShahady H, Al-Magedi AAS.   +7 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Stress first aid for the harm reduction workforce: pilot test results of an occupational stress intervention. [PDF]

BMC Public Health
Desai A, Rau J, Samora J, McCormick KA, Rochani H, Chang P, Westphal RJ, Watson PJ, Benzer JK, Claborn KR, Creech SK.   +10 more
europepmc   +1 more source