Results 271 to 280 of about 18,552,185 (409)

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

Assessment of Knowledge and Attitude Regarding First Aid Management of Road Traffic Accidents among Undergraduate Medical Students

, 1969
Rabia Qadeer, Surriyya Sarwat, Syeda GhadeerZehra Naqvi, Usman Shabbir, Aliza Babar   +4 more
openalex   +2 more sources

Improving support for people with mental health problems in China: a cluster randomised controlled trial of culturally adapted Mental Health First Aid training. [PDF]

Lancet Reg Health West Pac
Reavley N, Morgan AJ, Jorm AF, Kitchener B, Wang Y, Lu S, Li W, Kelly C, Oldenburg B, Zhao M, He Y.   +10 more
europepmc   +1 more source

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

Molecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Evaluating the impact of Mental Health First Aid (MHFA) training for UK construction workers [PDF]

, 2019
Hare, Billy, Janusonyte, Gabriele, Lawani, Kenneth, Lawrence, Maggie   +3 more
core   +1 more source

Validation and usability assessment of a mobile application on first aid for children for professionals in basic education. [PDF]

J Educ Health Promot
de Santana RCB, Oliveira MMC, de Souza ASC, Fonseca DS, Whitaker MCO, Magalhães BMBS, Gamba NCR, Rodrigues VMCP.   +7 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

First Aid in Neurological Diseases

, 1974
H Chigasaki, Atsushi Ishizawa
openalex   +2 more sources

Knowledge about first aid of childhood emergency conditions among caregivers attending primary care centers in Bahrain - A cross-sectional study. [PDF]

J Family Med Prim Care
Al Haddad HA, Alawainati M, Hasan HF, Husain HA, Mubarak S, Sanad AH.   +5 more
europepmc   +1 more source