Results 281 to 290 of about 18,552,185 (409)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir+2 more
wiley +1 more source
Imperial strategy of cancer cells through mitochondrial transfer
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley +1 more source
Importance and Obstacles of First Aid in Burn Injuries; A Letter to The Editor. [PDF]
Madadizadeh F, Afzal G.
europepmc +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir+12 more
wiley +1 more source
Psychological First Aid by AI: Proof-of-Concept and Comparative Performance of ChatGPT-4 and Gemini in Different Disaster Scenarios. [PDF]
Tan JT+7 more
europepmc +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He+8 more
wiley +1 more source
Psychological first aid for Ukrainian civilians: protocol and reflections on a volunteer international phone-based intervention. [PDF]
Shraga Y, Pushkarskaya H, Sarid O.
europepmc +1 more source