Results 281 to 290 of about 15,480,750 (322)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

A cross-sectional survey of first-aid kit equipment in a family in Sichuan, China. [PDF]

BMC Public Health
Wen D, Wan L, He H, Zhong Q, Jiang Q, Yang X, Zhang D, Shen Y.   +7 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

From digital harm to recovery: a multidisciplinary framework for First Aid after Online Sexual Abuse. [PDF]

Eur J Psychotraumatol
Knipschild R, Covers M, Bicanic IAE.
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Public Awareness Levels Regarding Cervical Spine Injury and the Suitable First Aid Response Among Adults in Makkah, Saudi Arabia. [PDF]

Int J Gen Med
Alghamdi FA, Alghamdi GA, Almatrafi WS, Alghamdi RF, Kelantan SR, Abdulsamad FF, Bawahab NS, Babateen O, Albar HT, Hariri NH.   +9 more
europepmc   +1 more source

Knowledge of local snakes, first-aid and prevention of snakebites among community health workers and community members in rural Malawi: A cross-sectional study. [PDF]

Trop Med Int Health
Aron MB, Munyaneza F, Rosenthal A, Dullie L, Krumkamp R, Ndarama E, Mailosi B, May J, Nhlema B, Sambani C, Hosemann D, Rae J, Rahden P, Blessmann J, Kreuels B.   +14 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Awareness of Burn Injury Prevention and First Aid Management Among Adults in Jazan, Saudi Arabia. [PDF]

Cureus
Abu Halimah J, Mojiri ME, Alhassan RA, Mobarki OA, Alharbi GH, Alharbi RH, Alshekh MM, Hakami RA, Hamithi DM, Hakami AH.   +9 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source