Results 61 to 70 of about 15,290,550 (298)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Background Paramedic students often face high levels of occupational anxiety due to heavy theoretical and clinical workloads. This anxiety can adversely affect academic performance, clinical competence and the quality of patient care.
Ahmet Doğan Kuday, Nazlıhan Tekin
doaj +1 more source
Objective: to evaluate the efficacy of injectable valproate (convulex) in patients with serial epileptic seizures and status epilepticus (SE) at the prehospital stage.Patients and methods.
A. V. Lebedeva +4 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Assessment of Mosul University Students' Knowledge about First Aid
Objectives: A descriptive study was designed to assess of Mosul university students' knowledge about first aid, and to assess the university students' knowledge about first aid cases (respiratory systems, circulatory systems, bleeding, trauma, burns ...
Hanaa Hussein Makhlef
doaj +1 more source

